Deregulated hedgehog pathway signaling is inhibited by the smoothened antagonist LDE225 (Sonidegib) in chronic phase chronic myeloid leukaemia
about
Preclinical approaches in chronic myeloid leukemia: from cells to systemsTherapeutic target discovery and drug development in cancer stem cells for leukemia and lymphoma: from bench to the clinic.Approaches for targeting self-renewal pathways in cancer stem cells: implications for hematological treatments.Mechanisms of Resistance to ABL Kinase Inhibition in Chronic Myeloid Leukemia and the Development of Next Generation ABL Kinase Inhibitors.PTCH1 is a reliable marker for predicting imatinib response in chronic myeloid leukemia patients in chronic phase.Enhanced targeting of CML stem and progenitor cells by inhibition of porcupine acyltransferase in combination with TKI.Non ABL-directed inhibitors as alternative treatment strategies for chronic myeloid leukemia.Concise Review: Chronic Myeloid Leukemia: Stem Cell Niche and Response to Pharmacologic Treatment.Overexpression of Tpl2 is linked to imatinib resistance and activation of MEK-ERK and NF-κB pathways in a model of chronic myeloid leukemia.Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewal
P2860
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P2860
Deregulated hedgehog pathway signaling is inhibited by the smoothened antagonist LDE225 (Sonidegib) in chronic phase chronic myeloid leukaemia
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Deregulated hedgehog pathway s ...... hase chronic myeloid leukaemia
@en
type
label
Deregulated hedgehog pathway s ...... hase chronic myeloid leukaemia
@en
prefLabel
Deregulated hedgehog pathway s ...... hase chronic myeloid leukaemia
@en
P2093
P2860
P50
P356
P1433
P1476
Deregulated hedgehog pathway s ...... hase chronic myeloid leukaemia
@en
P2093
Anuradha Tarafdar
Colin Nixon
David A Irvine
Heather Morrison
Helen Wheadon
Mhairi Copland
Paul W Manley
Ravi Bhatia
Tessa L Holyoake
P2860
P2888
P356
10.1038/SREP25476
P407
P577
2016-05-09T00:00:00Z