Negative and positive regulation in trans of gene expression from adeno-associated virus vectors in mammalian cells by a viral rep gene product
about
The adeno-associated virus type 2 regulatory proteins rep78 and rep68 interact with the transcriptional coactivator PC4.Efficient replication of adeno-associated virus type 2 vectors: a cis-acting element outside of the terminal repeats and a minimal sizeParvovirus replicationAnalysis of adeno-associated virus (AAV) wild-type and mutant Rep proteins for their abilities to negatively regulate AAV p5 and p19 mRNA levelsRegulation of adeno-associated virus gene expression in 293 cells: control of mRNA abundance and translationPartial purification of adeno-associated virus Rep78, Rep52, and Rep40 and their biochemical characterizationAlternate mRNA splicing is required for synthesis of adeno-associated virus VP1 capsid proteinReplication of adeno-associated virus in cells irradiated with UV light at 254 nmDetermination and analysis of the complete nucleotide sequence of human herpesvirusAdeno-associated virus type 2 rep protein inhibits human papillomavirus type 16 E2 recruitment of the transcriptional coactivator p300.Biochemical characterization of adeno-associated virus rep68 DNA helicase and ATPase activities.Analysis of the effects of charge cluster mutations in adeno-associated virus Rep68 protein in vitroA chimeric protein containing the N terminus of the adeno-associated virus Rep protein recognizes its target site in an in vivo assay.Negative regulation of the adeno-associated virus (AAV) P5 promoter involves both the P5 rep binding site and the consensus ATP-binding motif of the AAV Rep68 proteinUpstream AP1- and CREB-binding sites confer high basal activity on the adeno-associated virus type 5 capsid gene promoterIntermediates of adeno-associated virus type 2 assembly: identification of soluble complexes containing Rep and Cap proteins.Sequence requirements for binding of Rep68 to the adeno-associated virus terminal repeatsThe adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infection.Analysis of recombinant adeno-associated virus packaging and requirements for rep and cap gene products.The adeno-associated virus type 2 p40 promoter requires a proximal Sp1 interaction and a p19 CArG-like element to facilitate Rep transactivation.The cytotoxicity of the parvovirus minute virus of mice nonstructural protein NS1 is related to changes in the synthesis and phosphorylation of cell proteins.Encapsidation of adeno-associated virus type 2 Rep proteins in wild-type and recombinant progeny virions: Rep-mediated growth inhibition of primary human cellsIdentification of linear DNA sequences that specifically bind the adeno-associated virus Rep protein.Interaction of the adeno-associated virus Rep protein with a sequence within the A palindrome of the viral terminal repeat.In vivo resolution of circular plasmids containing concatemer junction fragments from minute virus of mice DNA and their subsequent replication as linear molecules.Adeno-associated virus Rep protein inhibits human immunodeficiency virus type 1 production in human cells.Restriction of porcine parvovirus replication in nonpermissive cells.Sequences required for coordinate induction of adeno-associated virus p19 and p40 promoters by Rep proteinAnalysis of mutations in adeno-associated virus Rep protein in vivo and in vitro.Mutational analysis of the adeno-associated virus rep gene.Parvovirus replication in normal and transformed human cells correlates with the nuclear translocation of the early protein NS1Adeno-associated virus rep protein synthesis during productive infectionMutation of lysine 405 to serine in the parvovirus H-1 NS1 abolishes its functions for viral DNA replication, late promoter trans activation, and cytotoxicity.Evidence for covalent attachment of the adeno-associated virus (AAV) rep protein to the ends of the AAV genome.Mutation of a consensus purine nucleotide binding site in the adeno-associated virus rep gene generates a dominant negative phenotype for DNA replicationPositive and negative regulation of the minute virus of mice P38 promoter.Regulated expression of the feline panleukopenia virus P38 promoter on extrachromosomal FPV/EBV chimeric plasmids.Factors that bind to adeno-associated virus terminal repeats.Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression.Both excision and replication of cloned autonomous parvovirus DNA require the NS1 (rep) protein.
P2860
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P2860
Negative and positive regulation in trans of gene expression from adeno-associated virus vectors in mammalian cells by a viral rep gene product
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Negative and positive regulati ...... ls by a viral rep gene product
@en
type
label
Negative and positive regulati ...... ls by a viral rep gene product
@en
prefLabel
Negative and positive regulati ...... ls by a viral rep gene product
@en
P2093
P2860
P356
P1476
Negative and positive regulati ...... ls by a viral rep gene product
@en
P2093
P2860
P304
P356
10.1128/MCB.6.8.2884
P407
P577
1986-08-01T00:00:00Z