about
Discovery and resupply of pharmacologically active plant-derived natural products: A reviewSingle-Base Pair Genome Editing in Human Cells by Using Site-Specific EndonucleasesFrom Gene Targeting to Genome Editing: Transgenic animals applications and beyondMolecular dynamics simulations of DNA-free and DNA-bound TAL effectorsA primer on the use of mouse models for identifying direct sex chromosome effects that cause sex differences in non-gonadal tissuesA robust TALENs system for highly efficient mammalian genome editing.Switching on sex: transcriptional regulation of the testis-determining gene SryGeneration of myostatin B knockout yellow catfish (Tachysurus fulvidraco) using transcription activator-like effector nucleasesMouse Y-linked Zfy1 and Zfy2 are expressed during the male-specific interphase between meiosis I and meiosis II and promote the 2nd meiotic division.Mutation of the Sp1 binding site in the 5' flanking region of SRY causes sex reversal in rabbits.Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases.Conceptual frameworks and mouse models for studying sex differences in physiology and disease: why compensation changes the game.Systematically labeling developmental stage-specific genes for the study of pancreatic β-cell differentiation from human embryonic stem cells.Sequencing the mouse Y chromosome reveals convergent gene acquisition and amplification on both sex chromosomes.TALE nickase-mediated SP110 knockin endows cattle with increased resistance to tuberculosis.Use of human pluripotent stem cells to study and treat retinopathiesGenetically engineered humanized mouse models for preclinical antibody studies.TALEN-Mediated Gene Disruption on Y Chromosome Reveals Critical Role of EIF2S3Y in Mouse SpermatogenesisGeneration of mutant mice via the CRISPR/Cas9 system using FokI-dCas9Direct production of XY(DMY-) sex reversal female medaka (Oryzias latipes) by embryo microinjection of TALENsApplied metabolomics in drug discovery.Complementary Critical Functions of Zfy1 and Zfy2 in Mouse Spermatogenesis and Reproduction.Mouse Y-Encoded Transcription Factor Zfy2 Is Essential for Sperm Head Remodelling and Sperm Tail Development.Spatial organization of heterologous metabolic system in vivo based on TALE.Site-Directed Genome Knockout in Chicken Cell Line and Embryos Can Use CRISPR/Cas Gene Editing Technology.Efficient nonmeiotic allele introgression in livestock using custom endonucleasesProduction of Sry knockout mouse using TALEN via oocyte injection.Rapid assembly of customized TALENs into multiple delivery systems.Comparison of TALEN scaffolds in Xenopus tropicalisThe Development of TALE Nucleases for Biotechnology.Binary recombinase systems for high-resolution conditional mutagenesis.Simultaneous gene editing by injection of mRNAs encoding transcription activator-like effector nucleases into mouse zygotes.Engineering subtle targeted mutations into the mouse genome.Translating human genetics into mouse: the impact of ultra-rapid in vivo genome editing.TALEN-mediated genome editing: prospects and perspectives.Generation of targeted mouse mutants by embryo microinjection of TALEN mRNA.TALEN-mediated genome engineering to generate targeted mice.Gene editing in birds takes flight.TALENs mediate efficient and heritable mutation of endogenous genes in the marine annelid Platynereis dumerilii.A history of genome editing in mammals.
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
TALEN-mediated editing of the mouse Y chromosome.
@en
type
label
TALEN-mediated editing of the mouse Y chromosome.
@en
prefLabel
TALEN-mediated editing of the mouse Y chromosome.
@en
P2093
P2860
P356
P1433
P1476
TALEN-mediated editing of the mouse Y chromosome.
@en
P2093
Adam J Bogdanove
Albert W Cheng
Chikdu S Shivalila
Daniel B Dadon
Daniel F Voytas
David C Page
G Grant Welstead
Haoyi Wang
Tatyana Pyntikova
Yueh-Chiang Hu
P2860
P2888
P304
P356
10.1038/NBT.2595
P577
2013-05-12T00:00:00Z