Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX. - Test2 - elhamkhani - TriplyDB

Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX.

Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX.

http://www.wikidata.org/entity/Q36936241

about

Chemical probes targeting epigenetic proteins: Applications beyond oncology.Sulforaphane suppresses EMT and metastasis in human lung cancer through miR-616-5p-mediated GSK3β/β-catenin signaling pathways.The Roles of Histone Demethylase Jmjd3 in Osteoblast Differentiation and Apoptosis.Long noncoding RNA HOTAIR promotes metastasis of renal cell carcinoma by up-regulating histone H3K27 demethylase JMJD3.Epigenetic modification in chromatin machinery and its deregulation in pediatric brain tumors: Insight into epigenetic therapies.Epigenetic Targeted Therapy for Diffuse Intrinsic Pontine Glioma The pharmacological role of histone demethylase JMJD3 inhibitor GSK-J4 on glioma cells.H3K27me3 dynamics dictate evolving uterine states in pregnancy and parturition.Calcitriol induces cell senescence of kidney cancer through JMJD3 mediated histone demethylation.Shifts in podocyte histone H3K27me3 regulate mouse and human glomerular disease.Transcription factor-dependent 'anti-repressive' mammalian enhancers exclude H3K27me3 from extended genomic domains.UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs The biological significance of histone modifiers in multiple myeloma: clinical applications Histone demethylase JARID1B/KDM5B promotes aggressiveness of non-small cell lung cancer and serves as a good prognostic predictor

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P2860

Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX.

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description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

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name

Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX.

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Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX.

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Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX.

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J.GDE.2016.03.010

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Current Opinion in Genetics & Development

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Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX.

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Carlos Alberto Martinez

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Kelly Marie Arcipowski

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Panagiotis Ntziachristos

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P2860

The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment

Translating the Histone Code

Crystal structure of the nucleosome core particle at 2.8 A resolution

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases

KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development

LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases

H3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic gene BCL2 determines ERα ligand dependency

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.

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59-67

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scholarly article

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10.1016/J.GDE.2016.03.010

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36

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2016-05-02T00:00:00Z

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