The V1-V3 region of a brain-derived HIV-1 envelope glycoprotein determines macrophage tropism, low CD4 dependence, increased fusogenicity and altered sensitivity to entry inhibitors
about
Compartmentalized human immunodeficiency virus type 1 originates from long-lived cells in some subjects with HIV-1-associated dementiaAlarmins and central nervous system inflammation in HIV-associated neurological disorders.The macrophage in HIV-1 infection: from activation to deactivation?Genetic variation and HIV-associated neurologic disease.Comparative analysis of the fusion efficiency elicited by the envelope glycoprotein V1-V5 regions derived from human immunodeficiency virus type 1 transmitted perinatally.HIV-1 replication in the central nervous system occurs in two distinct cell types.Variations in autologous neutralization and CD4 dependence of b12 resistant HIV-1 clade C env clones obtained at different time points from antiretroviral naïve Indian patients with recent infection.Defining differential genetic signatures in CXCR4- and the CCR5-utilizing HIV-1 co-linear sequences.A role for microRNA-155 modulation in the anti-HIV-1 effects of Toll-like receptor 3 stimulation in macrophages.Central nervous system compartmentalization of HIV-1 subtype C variants early and late in infection in young childrenLaser capture microdissection assessment of virus compartmentalization in the central nervous systems of macaques infected with neurovirulent simian immunodeficiency virusHIV-1 target cells in the CNS.Compartmentalized replication of R5 T cell-tropic HIV-1 in the central nervous system early in the course of infection.Viral determinants of HIV-1 macrophage tropism.Compartmentalization, Viral Evolution, and Viral Latency of HIV in the CNS.Correlation of the virological response to short-term maraviroc monotherapy with standard and deep-sequencing-based genotypic tropism prediction methods.Longitudinal Analysis of Cerebrospinal Fluid and Plasma HIV-1 Envelope Sequences Isolated From a Single Donor with HIV Asymptomatic Neurocognitive Impairment.Phenotypic Correlates of HIV-1 Macrophage Tropism.A species-specific amino acid difference in the macaque CD4 receptor restricts replication by global circulating HIV-1 variants representing viruses from recent infection.Conserved Role of an N-Linked Glycan on the Surface Antigen of Human Immunodeficiency Virus Type 1 Modulating Virus Sensitivity to Broadly Neutralizing Antibodies against the Receptor and Coreceptor Binding SitesEnvelope gene evolution and HIV-1 neuropathogenesis.Breast milk and in utero transmission of HIV-1 select for envelope variants with unique molecular signatures.Immune Responses in the Central Nervous System Are Anatomically Segregated in a Non-Human Primate Model of Human Immunodeficiency Virus Infection.Fate of microglia during HIV-1 infection: From activation to senescence?Compartmentalization and clonal amplification of HIV-1 variants in the cerebrospinal fluid during primary infection.Discordant patterns of tissue-specific genetic characteristics in the HIV-1 env gene from HIV-associated neurocognitive disorder (HAND) and non-HAND patients.Prediction of HIV-associated neurocognitive disorder (HAND) from three genetic features of envelope gp120 glycoprotein.HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency.
P2860
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P2860
The V1-V3 region of a brain-derived HIV-1 envelope glycoprotein determines macrophage tropism, low CD4 dependence, increased fusogenicity and altered sensitivity to entry inhibitors
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The V1-V3 region of a brain-de ...... ensitivity to entry inhibitors
@en
type
label
The V1-V3 region of a brain-de ...... ensitivity to entry inhibitors
@en
prefLabel
The V1-V3 region of a brain-de ...... ensitivity to entry inhibitors
@en
P2093
P2860
P356
P1433
P1476
The V1-V3 region of a brain-de ...... ensitivity to entry inhibitors
@en
P2093
Bianca Querido
Fiorella Rossi
Julio Martín-García
Manideepthi Nimmagadda
Simon Cocklin
P2860
P2888
P356
10.1186/1742-4690-5-89
P577
2008-10-06T00:00:00Z
P5875
P6179
1038968224