MECP2 genomic structure and function: insights from ENCODE
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Rett syndrome - biological pathways leading from MECP2 to disorder phenotypesAssociation of modified cytosines and the methylated DNA-binding protein MeCP2 with distinctive structural domains of lampbrush chromatinMECP2 and Associated Rett SyndromeA partial MECP2 duplication in a mildly affected adult male: a putative role for the 3' untranslated region in the MECP2 duplication phenotype.Astrocyte-specific regulation of hMeCP2 expression in Drosophila.Complexities of Rett syndrome and MeCP2Brain region-specific expression of MeCP2 isoforms correlates with DNA methylation within Mecp2 regulatory elements.MECP2, a gene associated with Rett syndrome in humans, shows conserved coding regions, independent Alu insertions, and a novel transcript across primate evolutionEpigenetics, autism spectrum, and neurodevelopmental disorders.Decitabine alters the expression of Mecp2 isoforms via dynamic DNA methylation at the Mecp2 regulatory elements in neural stem cells.The intervening domain from MeCP2 enhances the DNA affinity of the methyl binding domain and provides an independent DNA interaction site.MeCP2-Related Diseases and Animal Models.Rett syndrome and MeCP2.Reduced expression of MECP2 affects cell commitment and maintenance in neurons by triggering senescence: new perspective for Rett syndromeRett Syndrome Mutant Neural Cells Lacks MeCP2 Immunoreactive Bands.Methyl-CpG-Binding Protein 2 (MECP2) Polymorphism in Iranian Patients with Systemic Lupus Erythematosus.Association Study of MECP2 Gene Single Nucleotide Polymorphisms in Juvenile-Onset Systemic Lupus Erythematosus Patients from Iran.MeCP2 Deficiency Leads to Loss of Glial Kir4.1.Changes in the methylation status of DAT, SERT, and MeCP2 gene promoters in the blood cell in families exposed to alcohol during the periconceptional period.Neural stem cells from a mouse model of Rett syndrome are prone to senescence, show reduced capacity to cope with genotoxic stress, and are impaired in the differentiation process.
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MECP2 genomic structure and function: insights from ENCODE
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
MECP2 genomic structure and function: insights from ENCODE
@en
type
label
MECP2 genomic structure and function: insights from ENCODE
@en
prefLabel
MECP2 genomic structure and function: insights from ENCODE
@en
P2093
P2860
P921
P356
P1476
MECP2 genomic structure and function: insights from ENCODE
@en
P2093
Alka Saxena
David Ravine
Jasmine Singh
P2860
P304
P356
10.1093/NAR/GKN591
P407
P577
2008-09-27T00:00:00Z