about
Cytochrome P450 2J2 is highly expressed in hematologic malignant diseases and promotes tumor cell growthSingle-cell STAT5 signal transduction profiling in normal and leukemic stem and progenitor cell populations reveals highly distinct cytokine responsesDistinct gene-expression profiles characterize mammary tumors developed in transgenic mice expressing constitutively active and C-terminally truncated variants of STAT5.Recurrent expression signatures of cytokines and chemokines are present and are independently prognostic in acute myelogenous leukemia and myelodysplasiaWnt/Ca2+/NFAT signaling maintains survival of Ph+ leukemia cells upon inhibition of Bcr-Abl.Investigation and analysis of single nucleotide polymorphisms in Janus kinase/signal transducer and activator of transcription genes with leukemia.Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformationFunctional proteomic profiling of AML predicts response and survivalAltered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network.High expression of suppressor of cytokine signaling-2 predicts poor outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group.Functional RNAi screen targeting cytokine and growth factor receptors reveals oncorequisite role for interleukin-2 gamma receptor in JAK3-mutation-positive leukemia.SOCS1 and SOCS3 are expressed in mononuclear cells in human cytomegalovirus viremia after allogeneic hematopoietic stem cell transplantation.Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis.Signal transducer and activator of transcription 5b (Stat5b) serine 193 is a novel cytokine-induced phospho-regulatory site that is constitutively activated in primary hematopoietic malignancies.Aldose reductase inhibition prevents colon cancer growth by restoring phosphatase and tensin homolog through modulation of miR-21 and FOXO3a.Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5BSuppression of E-protein activity interferes with the development of BCR-ABL-mediated myeloproliferative diseaseA Standardized Chemically Modified Curcuma longa Extract Modulates IRAK-MAPK Signaling in Inflammation and Potentiates Cytotoxicity.Roles of SIRT1 in leukemogenesis.Bone resorption is regulated by cell-autonomous negative feedback loop of Stat5-Dusp axis in the osteoclast.De novo AML exhibits greater microenvironment dysregulation compared to AML with myelodysplasia-related changes.The possible diagnostic and prognostic use of systemic chemokine profiles in clinical medicine—the experience in acute myeloid leukemia from disease development and diagnosis via conventional chemotherapy to allogeneic stem cell transplantation.CXCL12/CXCR4 axis in the pathogenesis of acute lymphoblastic leukemia (ALL): a possible therapeutic target.Cell intrinsic and extrinsic regulation of leukemia cell metabolism.Loss of p300 accelerates MDS-associated leukemogenesis.The prognostic significance of serum and cerebrospinal fluid MMP-9, CCL2 and sVCAM-1 in leukemia CNS metastasis.Differences in proliferative capacity of primary human acute myelogenous leukaemia cells are associated with altered gene expression profiles and can be used for subclassification of patients.Circulating cytokines and small molecules follow distinct expression patterns in acute myeloid leukaemia.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Aberrant cytokine signaling in leukemia.
@en
type
label
Aberrant cytokine signaling in leukemia.
@en
prefLabel
Aberrant cytokine signaling in leukemia.
@en
P2860
P356
P1433
P1476
Aberrant cytokine signaling in leukemia.
@en
P2093
R A Van Etten
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210758
P407
P577
2007-10-01T00:00:00Z
P5875
P6179
1000222108