Activation and products of the cryptic secondary metabolite biosynthetic gene clusters by rifampin resistance (rpoB) mutations in actinomycetes.
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Biosynthesis of the Fluorinated Natural Product Nucleocidin in Streptomyces calvus Is Dependent on the bldA-Specified Leu-tRNA(UUA) Molecule.Combinatorial and high-throughput screening approaches for strain engineering.Activation and enhancement of Fredericamycin A production in deepsea-derived Streptomyces somaliensis SCSIO ZH66 by using ribosome engineering and response surface methodologyStructuring Microbial Metabolic Responses to Multiplexed Stimuli via Self-Organizing Metabolomics Maps.Rifampin Resistance rpoB Alleles or Multicopy Thioredoxin/Thioredoxin Reductase Suppresses the Lethality of Disruption of the Global Stress Regulator spx in Staphylococcus aureusActivation of Antibiotic Production in Bacillus spp. by Cumulative Drug Resistance Mutations.Improvement of daptomycin production in Streptomyces roseosporus through the acquisition of pleuromutilin resistance.Identification of two novel anti-fibrotic benzopyran compounds produced by engineered strains derived from Streptomyces xiamenensis M1-94P that originated from deep-sea sediments.Rifampicin-Resistance Mutations in the rpoB Gene in Bacillus velezensis CC09 have Pleiotropic Effects.The mthA mutation conferring low-level resistance to streptomycin enhances antibiotic production in Bacillus subtilis by increasing the S-adenosylmethionine pool sizeActivating the expression of bacterial cryptic genes by rpoB mutations in RNA polymerase or by rare earth elements.Resistance to rifampicin: a review.Spontaneous and induced mutations to rifampicin, streptomycin and spectinomycin resistances in actinomycetes: mutagenic mechanisms and applications for strain improvement.Genetic manipulation of secondary metabolite biosynthesis for improved production in Streptomyces and other actinomycetes.Progress in Understanding the Genetic Information and Biosynthetic Pathways behind Amycolatopsis Antibiotics, with Implications for the Continued Discovery of Novel Drugs.Prospecting for new bacterial metabolites: a glossary of approaches for inducing, activating and upregulating the biosynthesis of bacterial cryptic or silent natural products.Engineering microbial hosts for production of bacterial natural productsInsights into microbial cryptic gene activation and strain improvement: principle, application and technical aspects.Native and engineered promoters in natural product discovery.Endophytic actinobacteria: Diversity, secondary metabolism and mechanisms to unsilence biosynthetic gene clusters.Lincomycin at Subinhibitory Concentrations Potentiates Secondary Metabolite Production by Streptomyces spp.Imaging mass spectrometry reveals highly specific interactions between actinomycetes to activate specialized metabolic gene clusters.Secondary Metabolites Produced during the Germination of Streptomyces coelicolor.Discovery of a new diol-containing polyketide by heterologous expression of a silent biosynthetic gene cluster from Streptomyces lavendulae FRI-5.Ribosome engineering and fermentation optimization leads to overproduction of tiancimycin A, a new enediyne natural product from Streptomyces sp. CB03234.Gifted microbes for genome mining and natural product discovery.Applicability of ribosome engineering to vitamin B12 production by Propionibacterium shermanii.Characterization of representative rpoB gene mutations leading to a significant change in toyocamycin production of Streptomyces diastatochromogenes 1628.Metabolic perturbation to enhance polyketide and nonribosomal peptide antibiotic production using triclosan and ribosome-targeting drugs.Improved antibiotic production and silent gene activation in Streptomyces diastatochromogenes by ribosome engineering.Concepts and Methods to Access Novel Antibiotics from Actinomycetes.Synthetic Biology of Antibiotic ProductionActivation of microbial secondary metabolic pathways: Avenues and challenges
P2860
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P2860
Activation and products of the cryptic secondary metabolite biosynthetic gene clusters by rifampin resistance (rpoB) mutations in actinomycetes.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Activation and products of the ...... B) mutations in actinomycetes.
@en
type
label
Activation and products of the ...... B) mutations in actinomycetes.
@en
prefLabel
Activation and products of the ...... B) mutations in actinomycetes.
@en
P2093
P2860
P356
P1476
Activation and products of the ...... B) mutations in actinomycetes.
@en
P2093
Ken Kasahara
Kiriko Murakami
Rie Kugimiya
Yukinori Tanaka
Yutaka Hirose
P2860
P304
P356
10.1128/JB.00147-13
P407
P577
2013-04-19T00:00:00Z