Insulin-like growth factor-1 in CNS and cerebrovascular aging
about
Cerebral microhemorrhages: mechanisms, consequences, and prevention.Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neuronsInsulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype.Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats.IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive miceEndothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat.Growth hormone, insulin-like growth factor-1 and the aging brain.Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular agingAssociations between depressive symptoms and memory deficits vary as a function of insulin-like growth factor (IGF-1) levels in healthy older adults.Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging.The age factor in axonal repair after spinal cord injury: A focus on neuron-intrinsic mechanisms.Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline.GH and ageing: Pitfalls and new insights.IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis.Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes.Biological factors and age-dependence of primary motor cortex experimental plasticity.Distribution of growth hormone-responsive cells in the mouse brain.Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease.The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer.Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment.Connective tissue growth factor (CTGF) in age-related vascular pathologies.
P2860
Q30235220-335F0879-71D3-431F-907E-C86BA1BF7852Q33600513-777A9F8D-C6B7-43ED-8C1C-4BFE5E75D4ACQ33638938-EB6F4A81-0538-4A21-922C-DFC3B027E7DCQ34001695-949B6A66-0734-4049-8E89-DCA8E20C07BBQ34727298-30F4149D-D53A-4CF9-8B47-ABE57C343221Q34736776-183942DE-DC87-4499-B069-ACD9C553B1ADQ35305216-BE4ACD98-BEB1-41A4-88DE-9A1186BECFB2Q35661804-5186B76C-D6C9-4E0C-8AAC-755FE66A1EC1Q36410004-C810A983-B3C5-4DCE-9E0E-B4D96F4D5E06Q37718687-9F3C6520-4425-4549-A1C9-0421155E7C98Q38994143-9BB7EAC9-ADE1-4937-8544-A50C81D54A85Q39000464-7187C567-3CEB-4C34-BF06-512A9D2E6982Q39009007-FDEEDDF4-4722-447A-B59F-1BFCAF216E86Q39287747-BB863888-7A0E-41B2-994B-9985B7D3E76CQ41444071-7C7E0A1C-0B01-40E2-B3FB-8231A478C8A0Q41444120-5BA820B5-29C1-4920-A79E-BDEB12749D37Q49339947-132D63B3-FD7F-4B43-8B46-09929024560FQ52148308-CCF9951E-5282-4A24-84DF-7546FD6E661BQ52875341-72D406CF-6AAE-4B93-8043-8E7D16C3BD1EQ54192569-DA1427CE-4779-4C33-A82D-DF83A5DED487Q54921849-D304351F-7325-48DC-B03A-901512778014Q54997614-AC993692-D09F-4460-991D-9674989BFF5DQ55024983-AE12FEB0-DB3E-4FBD-89F8-7E70C92D0816
P2860
Insulin-like growth factor-1 in CNS and cerebrovascular aging
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Insulin-like growth factor-1 in CNS and cerebrovascular aging
@en
type
label
Insulin-like growth factor-1 in CNS and cerebrovascular aging
@en
prefLabel
Insulin-like growth factor-1 in CNS and cerebrovascular aging
@en
P2093
P2860
P356
P1476
Insulin-like growth factor-1 in CNS and cerebrovascular aging
@en
P2093
Anna Csiszar
Ferenc Deak
Nicole Ashpole
Peter Toth
Willard Freeman
William E Sonntag
Zoltan Ungvari
P2860
P356
10.3389/FNAGI.2013.00027
P577
2013-07-02T00:00:00Z