Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells
about
An integrated in vitro model of perfused tumor and cardiac tissueTumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces.Controlled breast cancer microarrays for the deconvolution of cellular multilayering and density effects upon drug responsesAlteration of cellular behavior and response to PI3K pathway inhibition by culture in 3D collagen gelsHigh-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cellsHypoxic tumor environments exhibit disrupted collagen I fibers and low macromolecular transportβ-Catenin-regulated ALDH1A1 is a target in ovarian cancer spheroidsStaged stromal extracellular 3D matrices differentially regulate breast cancer cell responses through PI3K and beta1-integrins.Three dimensional microfluidic cell arrays for ex vivo drug screening with mimicked vascular flow.Miniaturized pre-clinical cancer models as research and diagnostic tools.In vitro models of tumor vessels and matrix: engineering approaches to investigate transport limitations and drug delivery in cancer.Influence of the microenvironment on cell fate determination and migrationCarcinoma matrix controls resistance to cisplatin through talin regulation of NF-kBThe benefits and challenges associated with the use of drug delivery systems in cancer therapy3D collagen type I matrix inhibits the antimigratory effect of doxorubicin.HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment.A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening.Three-dimensional in vitro tumor models for cancer research and drug evaluation.Enhanced genetic instability and dasatinib sensitivity in mammary tumor cells lacking NEDD9Perlecan Domain V induces VEGf secretion in brain endothelial cells through integrin α5β1 and ERK-dependent signaling pathways.3D microchannel co-culture: method and biological validation.Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling.Integrin αβ1, αvβ, α6β effectors p130Cas, Src and talin regulate carcinoma invasion and chemoresistance.Prediction of individual response to anticancer therapy: historical and future perspectivesAnti-Inflammatory and Cytostatic Activities of a Parthenolide-Like Sesquiterpene Lactone from Cota palaestina subsp. syriaca.Fibroblast-Derived Extracellular Matrices: An Alternative Cell Culture System That Increases Metastatic Cellular PropertiesChallenges in pre-clinical testing of anti-cancer drugs in cell culture and in animal modelsSPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells.The mesenchymal tumor microenvironment: a drug-resistant niche.MEK Inhibitor Selumetinib (AZD6244; ARRY-142886) Prevents Lung Metastasis in a Triple-Negative Breast Cancer Xenograft ModelTissue dynamics spectroscopy for phenotypic profiling of drug effects in three-dimensional culture.Quantitative analysis of complex glioma cell migration on electrospun polycaprolactone using time-lapse microscopyIntracellular Doppler Signatures of Platinum Sensitivity Captured by Biodynamic Profiling in Ovarian Xenografts.Wharton's Jelly-Derived Mesenchymal Stromal Cells and Fibroblast-Derived Extracellular Matrix Synergistically Activate Apoptosis in a p21-Dependent Mechanism in WHCO1 and MDA MB 231 Cancer Cells In Vitro.Modeling pancreatic cancer with organoidsMicrofabricated polymeric vessel mimetics for 3-D cancer cell cultureFibroblast-Derived Extracellular Matrix Induces Chondrogenic Differentiation in Human Adipose-Derived Mesenchymal Stromal/Stem Cells in Vitro.Bioreactor-Based Tumor Tissue Engineering.Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells.Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells.
P2860
Q26822867-75D0EF6F-1970-487E-950F-6527A7FDEB29Q27316928-30EAB35B-27B0-4452-9770-865E57000C58Q28480895-842E0C01-F812-4F49-8454-DA7E1E59C0F5Q28484532-9D079AC8-E179-48F6-8F5D-048C952B1523Q28534624-4FB0827B-1A44-473C-91BB-AFB57452475AQ28537591-637A1466-F587-49F9-A8A8-E96ABF3F9147Q30370274-CDE84866-DAEE-40CD-822F-E567B031FE26Q30487084-A1FF8E71-1C8C-46B8-B3DE-447E03D58582Q30575882-63DB9EE9-D712-48DC-8F1D-5ECEF8C4F1FDQ33605145-40DD13C7-5783-4B3F-8FFC-B5D85AB8ADECQ33605281-C077F55F-33DF-414A-90B3-50F720F7EAA0Q33672091-A1F1417B-76B3-44EE-BA4E-9D575F99456AQ33947972-15A8B361-B09A-44D5-9FFE-20957DD10A0CQ33965271-7BE7FDAE-504D-4655-8DBC-E7A6F5173813Q34084025-CB97F873-A752-47FB-83B4-0BC104D796BDQ34111958-704BB152-6AAF-408B-BA05-F14577B6CD7EQ34143251-132606DF-4167-4BE5-A1BE-3B4CA8C77663Q34225333-6FA86CFD-1B6D-4F93-B331-E862BDFFED45Q34267936-4FD0D160-CDED-43CA-BD32-DBD6ED16A417Q34428518-D2FC415C-6102-4135-998B-121E33A6B924Q34512627-7EED9E72-D133-4068-8E3A-4E0863C6C5E1Q34727905-D5313BEF-EC89-4D36-8E10-20943F4819C1Q35008834-9EE0470D-3ABA-487C-AC0A-232A2A8BF99DQ35024682-36574C1E-05DA-4978-992F-E0A27AC6A579Q35674591-2BB19621-7904-49FB-83D2-8D407C878475Q35775737-F00E1B5B-C875-42C1-BA4C-38D94518AB6FQ36070093-41CA133A-4072-4666-8F03-711530A8BA3FQ36131297-FE8D8733-C1D4-475D-B2C7-3009EDA72531Q36187755-E94E3678-6430-4D38-8E50-7FAF30EC6586Q36359541-88C6C0C3-DAEB-4E77-B000-EE77EA44CA64Q36383804-FF626D06-8BAC-42DE-A5EC-7574E51056D4Q36398251-DA358A9A-6CA6-4D31-AF1D-66D5F04CDF54Q36432553-7DDA20FC-AE29-4CD9-BCAB-55EF0106DE22Q36532173-D7878CF3-96B8-456C-868D-53C4FACCADF8Q36842030-5592A7C2-F4BC-4FD5-866B-B841A8B2830DQ37137850-CB8432EF-997E-4139-87BE-C1F62D534555Q37209984-E342BE31-2F14-4800-B737-349255CBA05BQ37369652-02E4BB6D-F964-4068-9964-F9027157FFB4Q37435382-72FC6A08-C24B-48C5-B4FD-3BDBA33A199BQ37500307-83816887-33BE-4E13-9A56-7C68447FFD48
P2860
Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 06 March 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Fibroblast-derived 3D matrix d ...... siveness of human cancer cells
@en
Fibroblast-derived 3D matrix d ...... iveness of human cancer cells.
@nl
type
label
Fibroblast-derived 3D matrix d ...... siveness of human cancer cells
@en
Fibroblast-derived 3D matrix d ...... iveness of human cancer cells.
@nl
prefLabel
Fibroblast-derived 3D matrix d ...... siveness of human cancer cells
@en
Fibroblast-derived 3D matrix d ...... iveness of human cancer cells.
@nl
P2093
P2860
P1433
P1476
Fibroblast-derived 3D matrix d ...... siveness of human cancer cells
@en
P2093
Acacia Lamb
Edna Cukierman
Erica A Golemis
Ilya Serebriiskii
Remedios Castelló-Cros
P2860
P304
P356
10.1016/J.MATBIO.2008.02.008
P577
2008-03-06T00:00:00Z