Twist1 homodimers enhance FGF responsiveness of the cranial sutures and promote suture closure
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Nonsense mutations of the bHLH transcription factor TWIST2 found in Setleis Syndrome patients cause dysregulation of periostinMicroRNA Regulation of Epithelial to Mesenchymal TransitionA Genetic-Pathophysiological Framework for CraniosynostosisThe emerging role of Twist proteins in hematopoietic cells and hematological malignanciesNormal and disease-related biological functions of Twist1 and underlying molecular mechanismsSignaling mechanisms implicated in cranial sutures pathophysiology: CraniosynostosisMultiple congenital malformations of Wolf-Hirschhorn syndrome are recapitulated in Fgfrl1 null miceEarly onset of craniosynostosis in an Apert mouse model reveals critical features of this pathologyTwist1 Is Essential for Tooth Morphogenesis and Odontoblast DifferentiationA newly described bovine type 2 scurs syndrome segregates with a frame-shift mutation in TWIST1Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2(+P253R) mice.Destabilization of the TWIST1/E12 complex dimerization following the R154P point-mutation of TWIST1: an in silico approach.Timed deletion of Twist1 in the limb bud reveals age-specific impacts on autopod and zeugopod patterningNeural crest cell signaling pathways critical to cranial bone development and pathology.Twist1- and Twist2-haploinsufficiency results in reduced bone formation.Twist1 directly regulates genes that promote cell proliferation and migration in developing heart valvesEMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice.Hand1 phosphoregulation within the distal arch neural crest is essential for craniofacial morphogenesis.Computational modeling of the bHLH domain of the transcription factor TWIST1 and R118C, S144R and K145E mutantsRedundant or separate entities?--roles of Twist1 and Twist2 as molecular switches during gene transcriptionEffects of thyroxine exposure on osteogenesis in mouse calvarial pre-osteoblasts.Structure-function studies of the bHLH phosphorylation domain of TWIST1 in prostate cancer cellsCritical role for TWIST1 in the induction of human uterine decidualization.Jagged1 functions downstream of Twist1 in the specification of the coronal suture and the formation of a boundary between osteogenic and non-osteogenic cellsRegulation of cranial morphogenesis and cell fate at the neural crest-mesoderm boundary by engrailed 1.Closing the Gap: Genetic and Genomic Continuum from Syndromic to Nonsyndromic Craniosynostoses.Frontal Bone Insufficiency in Gsk3β Mutant Mice.Palatal and oral manifestations of Muenke syndrome (FGFR3-related craniosynostosis).Basic helix-loop-helix transcription factor Twist1 inhibits transactivator function of master chondrogenic regulator Sox9.Negative Regulatory Role of TWIST1 on SNAIL Gene Expression.Evolution of the Twist Subfamily Vertebrate Proteins: Discovery of a Signature Motif and Origin of the Twist1 Glycine-Rich Motifs in the Amino-Terminus Disordered Domain.Id1 Expression Level Determines the Differentiation of Human Dental Pulp Stem Cells.Id1 overexpression is independent of repression and epigenetic silencing of tumor suppressor genes in melanomaMesodermal expression of Fgfr2S252W is necessary and sufficient to induce craniosynostosis in a mouse model of Apert syndrome.The Heterodimeric TWIST1-E12 Complex Drives the Oncogenic Potential of TWIST1 in Human Mammary Epithelial CellsUnderstanding craniosynostosis as a growth disorderEphA4 as an effector of Twist1 in the guidance of osteogenic precursor cells during calvarial bone growth and in craniosynostosisA twist of insight - the role of Twist-family bHLH factors in development.Interhelical loops within the bHLH domain are determinant in maintaining TWIST1-DNA complexes.A bHLH code for cardiac morphogenesis.
P2860
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P2860
Twist1 homodimers enhance FGF responsiveness of the cranial sutures and promote suture closure
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 08 April 2008
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Twist1 homodimers enhance FGF ...... res and promote suture closure
@en
Twist1 homodimers enhance FGF ...... es and promote suture closure.
@nl
type
label
Twist1 homodimers enhance FGF ...... res and promote suture closure
@en
Twist1 homodimers enhance FGF ...... es and promote suture closure.
@nl
prefLabel
Twist1 homodimers enhance FGF ...... res and promote suture closure
@en
Twist1 homodimers enhance FGF ...... es and promote suture closure.
@nl
P2093
P2860
P1476
Twist1 homodimers enhance FGF ...... res and promote suture closure
@en
P2093
Douglas B Spicer
Jeannette Connerney
Karen Dowell
Miguel A Mercado
Robert E Friesel
Viktoria Andreeva
Volkhard Lindner
Xuehei Yang
Yael Leshem
P2860
P304
P356
10.1016/J.YDBIO.2008.03.037
P407
P577
2008-04-08T00:00:00Z