Subchronic glucocorticoid receptor inhibition rescues early episodic memory and synaptic plasticity deficits in a mouse model of Alzheimer's disease.

Subchronic glucocorticoid receptor inhibition rescues early episodic memory and synaptic plasticity deficits in a mouse model of Alzheimer's disease.

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http://www.wikidata.org/entity/Q37024857
Locus Coeruleus, norepinephrine and Aβ peptides in Alzheimer's diseaseThe caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function.Positive and negative early life experiences differentially modulate long term survival and amyloid protein levels in a mouse model of Alzheimer's disease.Age-related synaptic dysfunction in Tg2576 mice starts as a failure in early long-term potentiation which develops into a full abolishment of late long-term potentiation.Physiological and pathophysiological control of synaptic GluN2B-NMDA receptors by the C-terminal domain of amyloid precursor protein.Enhanced Hypothalamic NMDA Receptor Activity Contributes to Hyperactivity of HPA Axis in Chronic Stress in Male Rats.Targeting glucocorticoid receptors prevents the effects of early life stress on amyloid pathology and cognitive performance in APP/PS1 mice.The relationship between stress and Alzheimer's disease.Central Role of Glucocorticoid Receptors in Alzheimer's Disease and Depression
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Subchronic glucocorticoid receptor inhibition rescues early episodic memory and synaptic plasticity deficits in a mouse model of Alzheimer's disease.

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http://www.wikidata.org/entity/Q37024857
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 27 January 2015
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Subchronic glucocorticoid rece ...... model of Alzheimer's disease.
@en
Subchronic glucocorticoid rece ...... model of Alzheimer's disease.
@nl
type
label
Subchronic glucocorticoid rece ...... model of Alzheimer's disease.
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Subchronic glucocorticoid rece ...... model of Alzheimer's disease.
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prefLabel
Subchronic glucocorticoid rece ...... model of Alzheimer's disease.
@en
Subchronic glucocorticoid rece ...... model of Alzheimer's disease.
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Subchronic glucocorticoid rece ...... e model of Alzheimer's disease
@en
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932