Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2
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Recent Advances in the Study of Bipolar/Rod-Shaped Microglia and their Roles in Neurodegeneration.The implication of neuronimmunoendocrine (NIE) modulatory network in the pathophysiologic process of Parkinson's disease.Let's make microglia great again in neurodegenerative disorders.α-Synuclein fibrils recruit peripheral immune cells in the rat brain prior to neurodegeneration.TLR4 and TLR2 activation is differentially associated with age during Parkinson's disease.Lack of PINK1 alters glia innate immune responses and enhances inflammation-induced, nitric oxide-mediated neuron death.Integrin CD11b mediates α-synuclein-induced activation of NADPH oxidase through a Rho-dependent pathway.Silencing Alpha Synuclein in Mature Nigral Neurons Results in Rapid Neuroinflammation and Subsequent Toxicity.Toll-Like Receptor 2 Signaling and Current Approaches for Therapeutic Modulation in Synucleinopathies.Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's diseaseRole of Microglia TLRs in NeurodegenerationThe Healing Effect of Human Milk Fat Globule-EGF Factor 8 Protein (MFG-E8) in A Rat Model of Parkinson's DiseaseModel Senescent Microglia Induce Disease Related Changes in α-Synuclein Expression and Activity
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Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 June 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2
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Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2.
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type
label
Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2
@en
Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2.
@nl
prefLabel
Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2
@en
Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2.
@nl
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Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2
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Changyoun Kim
He-Jin Lee
Seung-Jae Lee
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P304
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10.5607/EN.2016.25.3.113
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2016-06-08T00:00:00Z