Cell signaling and nuclear receptors: new opportunities for molecular pharmaceuticals in liver disease.
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PGC-1alpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis.Post-translational modification of pregnane x receptor.Role of high-fat diet in regulation of gene expression of drug metabolizing enzymes and transporters.Serine 350 of human pregnane X receptor is crucial for its heterodimerization with retinoid X receptor alpha and transactivation of target genes in vitro and in vivoProtection of primary neurons and mouse brain from Alzheimer's pathology by molecular tweezers.Possible regulation of genes associated with intracellular signaling cascade in rat liver regeneration.Sensitivity of lipid metabolism and insulin signaling to genetic alterations in hepatic peroxisome proliferator-activated receptor-gamma coactivator-1alpha expressionBile acids as regulatory molecules.Bile Acid sulfation: a pathway of bile acid elimination and detoxification.A systematic analysis of predicted phosphorylation sites within the human pregnane X receptor protein.High glucose upregulates BACE1-mediated Aβ production through ROS-dependent HIF-1α and LXRα/ABCA1-regulated lipid raft reorganization in SK-N-MC cells.Long-term virus-induced alterations of CYP3A-mediated drug metabolism: a look at the virology, immunology and molecular biology of a multi-faceted problem.Zinc and alcoholic liver disease.Post-translational and post-transcriptional modifications of pregnane X receptor (PXR) in regulation of the cytochrome P450 superfamily.A SUMO-acetyl switch in PXR biology.Gold nanoparticles functionalized with peptides for specific affinity aggregation assays of estrogen receptors and their agonists.Cyclic AMP-dependent protein kinase signaling modulates pregnane x receptor activity in a species-specific manner.Expression profiles uncover the relationship between erythropoietin and cell proliferation in rat hepatocytes after a partial hepatectomy.Role of c-Jun-N-terminal kinase in pregnane X receptor-mediated induction of human cytochrome P4503A4 in vitro.Fatty liver is associated with impaired activity of PPARγ-coactivator 1α (PGC1α) and mitochondrial biogenesis in mice.The cross-sectional association between insulin resistance and circulating complement C3 is partly explained by plasma alanine aminotransferase, independent of central obesity and general inflammation (the CODAM study)
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Cell signaling and nuclear receptors: new opportunities for molecular pharmaceuticals in liver disease.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 27 December 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Cell signaling and nuclear rec ...... rmaceuticals in liver disease.
@en
Cell signaling and nuclear rec ...... rmaceuticals in liver disease.
@nl
type
label
Cell signaling and nuclear rec ...... rmaceuticals in liver disease.
@en
Cell signaling and nuclear rec ...... rmaceuticals in liver disease.
@nl
prefLabel
Cell signaling and nuclear rec ...... rmaceuticals in liver disease.
@en
Cell signaling and nuclear rec ...... rmaceuticals in liver disease.
@nl
P2860
P356
P1476
Cell signaling and nuclear rec ...... rmaceuticals in liver disease.
@en
P2093
Jeff L Staudinger
Kristin Lichti
P2860
P356
10.1021/MP700098C
P407
P577
2007-12-27T00:00:00Z