Peptide-mediated inhibition of mitogen-activated protein kinase-activated protein kinase-2 ameliorates bleomycin-induced pulmonary fibrosis - Test2 - elhamkhani - TriplyDB

Peptide-mediated inhibition of mitogen-activated protein kinase-activated protein kinase-2 ameliorates bleomycin-induced pulmonary fibrosis

Peptide-mediated inhibition of mitogen-activated protein kinase-activated protein kinase-2 ameliorates bleomycin-induced pulmonary fibrosis

http://www.wikidata.org/entity/Q37056483

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MMI-0100 inhibits cardiac fibrosis in myocardial infarction by direct actions on cardiomyocytes and fibroblasts via MK2 inhibition.Matrix stiffness affects endocytic uptake of MK2-inhibitor peptides Plasma Soluble Receptor for Advanced Glycation End Products in Idiopathic Pulmonary Fibrosis.Crosstalk between TGF-β1 and complement activation augments epithelial injury in pulmonary fibrosis.Targeting Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2, MK2): Medicinal Chemistry Efforts To Lead Small Molecule Inhibitors to Clinical Trials Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosis.Pivotal Role of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 in Inflammatory Pulmonary Diseases.Stress-dependent phosphorylation of myocardin-related transcription factor A (MRTF-A) by the p38(MAPK)/MK2 axis Emerging therapeutic interventions for idiopathic pulmonary fibrosis.Dissecting fibrosis: therapeutic insights from the small-molecule toolbox.Fibroblast-Specific Genetic Manipulation of p38 Mitogen-Activated Protein Kinase In Vivo Reveals Its Central Regulatory Role in Fibrosis.Lrp5/β-Catenin Signaling Controls Lung Macrophage Differentiation and Inhibits Resolution of Fibrosis.Characterization of endocytic uptake of MK2-inhibitor peptides.Cholesterol-modified Hydroxychloroquine-loaded Nanocarriers in Bleomycin-induced Pulmonary Fibrosis.Nebulized Delivery of the MAPKAP Kinase 2 Peptide Inhibitor MMI-0100 Protects Against Ischemia-Induced Systolic Dysfunction.MMI-0100 Inhibits Cardiac Fibrosis in a Mouse Model Overexpressing Cardiac Myosin Binding Protein C.Drugs and Targets in Fibrosis.IL-17A deficiency mitigates bleomycin-induced complement activation during lung fibrosis.

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Peptide-mediated inhibition of mitogen-activated protein kinase-activated protein kinase-2 ameliorates bleomycin-induced pulmonary fibrosis

http://www.wikidata.org/entity/Q37056483

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article científic

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article scientifique

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bilimsel makale

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scientific article published on July 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Peptide-mediated inhibition of ...... cin-induced pulmonary fibrosis

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Peptide-mediated inhibition of ...... in-induced pulmonary fibrosis.

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type

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Peptide-mediated inhibition of ...... cin-induced pulmonary fibrosis

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Peptide-mediated inhibition of ...... in-induced pulmonary fibrosis.

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Peptide-mediated inhibition of ...... cin-induced pulmonary fibrosis

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Peptide-mediated inhibition of ...... in-induced pulmonary fibrosis.

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RCMB.2012-0389OC

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American Journal of Respiratory Cell and Molecular Biology

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Peptide-mediated inhibition of ...... cin-induced pulmonary fibrosis

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Alyssa Panitch

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Amanda Fisher

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Cynthia Lander

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David S Wilkes

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Elizabeth A Mickler

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George E Sandusky

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Hongmei Gu

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Oscar W Cummings

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Ragini Vittal

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P2860

BMP-7 does not protect against bleomycin-induced lung or skin fibrosis

Enhanced IL-1 beta and tumor necrosis factor-alpha release and messenger RNA expression in macrophages from idiopathic pulmonary fibrosis or after asbestos exposure

Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation

p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils

The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling

An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management

MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels

Focal adhesion features during myofibroblastic differentiation are controlled by intracellular and extracellular factors.

Bleomycin and IL-1beta-mediated pulmonary fibrosis is IL-17A dependent.

Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in mice

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47-57

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scholarly article

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10.1165/RCMB.2012-0389OC

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1

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2013-07-01T00:00:00Z

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23470623

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pulmonary fibrosis

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3727887

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