about
Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathwayTransient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-Beta mediated mechanism in a mouse xenograft model of breast cancerRaf kinases in cancer-roles and therapeutic opportunitiesLASP1-S100A11 axis promotes colorectal cancer aggressiveness by modulating TGFβ/Smad signalingUSP26 regulates TGF-β signaling by deubiquitinating and stabilizing SMAD7Cytokine-driven loss of plasmacytoid dendritic cell function in chronic lymphocytic leukemiaModulation of circulating protein biomarkers following TRC105 (anti-endoglin antibody) treatment in patients with advanced cancer.IL-10 and TGF-beta redundantly protect against severe liver injury and mortality during acute schistosomiasisStrong impact of TGF-β1 gene polymorphisms on breast cancer risk in Indian women: a case-control and population-based study.NF-κB induces miR-148a to sustain TGF-β/Smad signaling activation in glioblastoma.Loss of RAB1B promotes triple-negative breast cancer metastasis by activating TGF-β/SMAD signalingTGF-β induces miR-182 to sustain NF-κB activation in glioma subsets.The harmonies played by TGF-β in stem cell biology.Stromal Modulators of TGF-β in Cancer.TGF-beta signalling and immunity in prostate tumourigenesis.Prime-boost immunization by both DNA vaccine and oncolytic adenovirus expressing GM-CSF and shRNA of TGF-β2 induces anti-tumor immune activationTRAF4 mediates activation of TGF-β signaling and is a biomarker for oncogenesis in breast cancer.Overactivation of the TGF-β pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells.Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis.CCAAT enhancer binding protein β has a crucial role in regulating breast cancer cell growth via activating the TGF-β-Smad3 signaling pathway.Unusual early-stage pancreatic sarcomatoid carcinoma.The HPV16 E6 oncoprotein and UVB irradiation inhibit the tumor suppressor TGFβ pathway in the epidermis of the K14E6 transgenic mouse.The TGFβ pathway stimulates ovarian cancer cell proliferation by increasing IGF1R levels.Targeting TGF-beta in prostate cancer: therapeutic possibilities during tumor progression
P2860
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P2860
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
The TGFBeta pathway as a therapeutic target in cancer.
@en
The TGFBeta pathway as a therapeutic target in cancer.
@nl
type
label
The TGFBeta pathway as a therapeutic target in cancer.
@en
The TGFBeta pathway as a therapeutic target in cancer.
@nl
prefLabel
The TGFBeta pathway as a therapeutic target in cancer.
@en
The TGFBeta pathway as a therapeutic target in cancer.
@nl
P1476
The TGFBeta pathway as a therapeutic target in cancer
@en
P2093
P2860
P2888
P356
10.1007/S12094-008-0148-2
P50
P577
2008-01-01T00:00:00Z