The DAF-2 insulin-like signaling pathway independently regulates aging and immunity in C. elegans
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Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebratesDistinct pathogenesis and host responses during infection of C. elegans by P. aeruginosa and S. aureusA functional genomic screen for evolutionarily conserved genes required for lifespan and immunity in germline-deficient C. elegansConserved nutrient sensor O-GlcNAc transferase is integral to C. elegans pathogen-specific immunityGenome-wide analysis of germline signaling genes regulating longevity and innate immunity in the nematode Pristionchus pacificusEGL-9 controls C. elegans host defense specificity through prolyl hydroxylation-dependent and -independent HIF-1 pathwaysProhibitin-mediated lifespan and mitochondrial stress implicate SGK-1, insulin/IGF and mTORC2 in C. elegansThe role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogasterPseudomonas aeruginosa disrupts Caenorhabditis elegans iron homeostasis, causing a hypoxic response and deathCaenorhabditis is a metazoan host for LegionellaWWP-1 is a novel modulator of the DAF-2 insulin-like signaling network involved in pore-forming toxin cellular defenses in Caenorhabditis elegans.The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity.Caenorhabditis elegans behavioral genetics: where are the knobs?Functional characterization of thioredoxin 3 (TRX-3), a Caenorhabditis elegans intestine-specific thioredoxin.The Natural Biotic Environment of Caenorhabditis elegans.Identification of ATF-7 and the insulin signaling pathway in the regulation of metallothionein in C. elegans suggests roles in aging and reactive oxygen species.A comprehensive analysis of gene expression changes provoked by bacterial and fungal infection in C. elegans.Exploring the function of protein kinases in schistosomes: perspectives from the laboratory and from comparative genomics.Systemic and cell intrinsic roles of Gqalpha signaling in the regulation of innate immunity, oxidative stress, and longevity in Caenorhabditis elegans.Model systems to the rescue: The relationship between aging and innate immunityInsulin/FOXO signaling regulates ovarian prostaglandins critical for reproduction.InAKTivation of insulin/IGF-1 signaling by dephosphorylation.Age-associated changes in expression of small, noncoding RNAs, including microRNAs, in C. elegans.A muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function, and life span in Drosophila.The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity.Plasmodium falciparum suppresses the host immune response by inducing the synthesis of insulin-like peptides (ILPs) in the mosquito Anopheles stephensiCytoplasmic LSM-1 protein regulates stress responses through the insulin/IGF-1 signaling pathway in Caenorhabditis elegansInnate immunity mediated longevity and longevity induced by germ cell removal converge on the C-type lectin domain protein IRG-7.Genome-Wide RNAi Longevity Screens in Caenorhabditis elegans.Modulation of Caenorhabditis elegans infection sensitivity by the LIN-7 cell junction proteinNoncanonical control of C. elegans germline apoptosis by the insulin/IGF-1 and Ras/MAPK signaling pathwaysA Stenotrophomonas maltophilia Strain Evades a Major Caenorhabditis elegans Defense Pathway.Immunosenescence in vertebrates and invertebratesDairy Propionibacterium extends the mean lifespan of Caenorhabditis elegans via activation of the innate immune system.Ultraviolet-A triggers photoaging in model nematode Caenorhabditis elegans in a DAF-16 dependent pathway.DAF-2 and ERK couple nutrient availability to meiotic progression during Caenorhabditis elegans oogenesis.Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: roles for GATA factors and lipid gene regulators.99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Caenorhabditis elegans as a model to study tissues involved in host immunity and microbial pathogenesis.Genetic and molecular analysis of nematode-microbe interactions.Strength in numbers: "Omics" studies of C. elegans innate immunity.
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The DAF-2 insulin-like signaling pathway independently regulates aging and immunity in C. elegans
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 08 September 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The DAF-2 insulin-like signali ...... ing and immunity in C. elegans
@en
The DAF-2 insulin-like signali ...... ng and immunity in C. elegans.
@nl
type
label
The DAF-2 insulin-like signali ...... ing and immunity in C. elegans
@en
The DAF-2 insulin-like signali ...... ng and immunity in C. elegans.
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prefLabel
The DAF-2 insulin-like signali ...... ing and immunity in C. elegans
@en
The DAF-2 insulin-like signali ...... ng and immunity in C. elegans.
@nl
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The DAF-2 insulin-like signali ...... ing and immunity in C. elegans
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Eric A Evans
Man-Wah Tan
Will C Chen
P2860
P304
P356
10.1111/J.1474-9726.2008.00435.X
P577
2008-09-08T00:00:00Z