Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis - Test2 - elhamkhani - TriplyDB

Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis

Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis

http://www.wikidata.org/entity/Q37073732

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From bending DNA to diabetes: the curious case of HMGA1 Nonalcoholic fatty liver disease: a comprehensive review of a growing epidemic Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance Genetic Rodent Models of Obesity-Associated Ovarian Dysfunction and Subfertility: Insights into Polycystic Ovary Syndrome Liver fibrosis in human immunodeficiency virus/hepatitis C virus coinfection: Diagnostic methods and clinical impact.Does Diacylglycerol Accumulation in Fatty Liver Disease Cause Hepatic Insulin Resistance?Pathway-selective insulin resistance and metabolic disease: the importance of nutrient flux Lessons from mouse models of high-fat diet-induced NAFLD Pathogenesis of the metabolic syndrome: insights from monogenic disorders How Useful Are Monogenic Rodent Models for the Study of Human Non-Alcoholic Fatty Liver Disease?Nonalcoholic fatty liver disease - A multisystem disease?Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis Impaired-inactivation of FoxO1 contributes to glucose-mediated increases in serum very low-density lipoprotein E4orf1: a novel ligand that improves glucose disposal in cell culture Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression.Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis Mutations disrupting the Kennedy phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver disease Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans.Mice deficient in group VIB phospholipase A2 (iPLA2gamma) exhibit relative resistance to obesity and metabolic abnormalities induced by a Western diet.Treatment of type B insulin resistance: a novel approach to reduce insulin receptor autoantibodies.Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance.Genetic defects in human pericentrin are associated with severe insulin resistance and diabetes.Nonalcoholic Fatty liver disease: pathogenesis and therapeutics from a mitochondria-centric perspective.Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity.Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance.Human lipodystrophies: genetic and acquired diseases of adipose tissue.Genetic determinants of hepatic steatosis in man.Founder effect in the Horn of Africa for an insulin receptor mutation that may impair receptor recycling Template to improve glycemic control without reducing adiposity or dietary fat.Mitochondrial dysfunction in patients with primary congenital insulin resistance.Coinfection with HIV-1 and HCV--a one-two punch.Genetics in endocrinology: genetic forms of severe insulin resistance: what endocrinologists should know.Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis.Low circulating levels of IGF-1 in healthy adults are associated with reduced β-cell function, increased intramyocellular lipid, and enhanced fat utilization during fasting.Human fatty liver disease: old questions and new insights Pathogenesis of selective insulin resistance in isolated hepatocytes.Prevalence of prediabetes and diabetes and metabolic profile of patients with nonalcoholic fatty liver disease (NAFLD).Mechanistic insights revealed by lipid profiling in monogenic insulin resistance syndromes.The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans Severe insulin resistance and hypertriglyceridemia after childhood total body irradiation.

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Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis

http://www.wikidata.org/entity/Q37073732

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 26 January 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis

@en

Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis.

@nl

type

label

Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis

@en

Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis.

@nl

prefLabel

Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis

@en

Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis.

@nl

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P1433

Journal of Clinical Investigation

P1476

Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis

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Alessandra Vottero

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Claire A Adams

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Dipak Kanabar

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Elaine K Cochran

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Les Bluck

http://www.w3.org/2001/XMLSchema#string

Maria A Soos

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Paul Durrington

http://www.w3.org/2001/XMLSchema#string

Peter R Murgatroyd

http://www.w3.org/2001/XMLSchema#string

Phillip Gorden

http://www.w3.org/2001/XMLSchema#string

Sarah Jackson

http://www.w3.org/2001/XMLSchema#string

P2860

IRS1-independent defects define major nodes of insulin resistance

Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease.

Java-based graphical user interface for the MRUI quantitation package.

Improved method for accurate and efficient quantification of MRS data with use of prior knowledge

Approximation of total visceral adipose tissue with a single magnetic resonance image

Insulin resistance and cardiovascular disease.

Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation

Acquired and inherited lipodystrophies.

Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis

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315-322

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scholarly article

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10.1172/JCI37432

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2

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119

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Robert K Semple

Stephen O'Rahilly

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2009-01-26T00:00:00Z

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19164855

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2631303

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