The organic cation transporter, OCTN1, expressed in the human heart, potentiates antagonism of the HERG potassium channel
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The role of transporters in toxicity and diseaseDrug- and non-drug-associated QT interval prolongation.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?Selective regulation of cardiac organic cation transporter novel type 2 (OCTN2) in dilated cardiomyopathyPharmacogenetics of Potassium Channel Blockers.Modulation of drug block of the cardiac potassium channel KCNA5 by the drug transporters OCTN1 and MDR1.Structural isomerization of synephrine influences its uptake and ensuing glutathione depletion in rat-isolated cardiomyocytes.Molecular basis of hERG potassium channel blockade by the class Ic antiarrhythmic flecainide.The dual-targeted HER1/HER2 tyrosine kinase inhibitor lapatinib strongly potentiates the cardiac myocyte-damaging effects of doxorubicin.
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P2860
The organic cation transporter, OCTN1, expressed in the human heart, potentiates antagonism of the HERG potassium channel
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The organic cation transporter ...... of the HERG potassium channel
@en
The organic cation transporter ...... of the HERG potassium channel.
@nl
type
label
The organic cation transporter ...... of the HERG potassium channel
@en
The organic cation transporter ...... of the HERG potassium channel.
@nl
prefLabel
The organic cation transporter ...... of the HERG potassium channel
@en
The organic cation transporter ...... of the HERG potassium channel.
@nl
P2093
P2860
P1476
The organic cation transporter ...... of the HERG potassium channel
@en
P2093
Brian F McBride
Dan M Roden
Kathleen M Giacomini
Richard B Kim
Thomas J Urban
P2860
P356
10.1097/FJC.0B013E3181ABC288
P407
P577
2009-07-01T00:00:00Z