Highly complementary target RNAs promote release of guide RNAs from human Argonaute2
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Anatomy of RISC: how do small RNAs and chaperones activate Argonaute proteins?When RNA and protein degradation pathways meetAgo1 Interacts with RNA polymerase II and binds to the promoters of actively transcribed genes in human cancer cellsAnti-miRs competitively inhibit microRNAs in Argonaute complexesRNA-mediated degradation of microRNAs: A widespread viral strategy?Obstacles and opportunities in the functional analysis of extracellular vesicle RNA - an ISEV position paperNon-canonical targets destabilize microRNAs in human ArgonautesMultifunctional aptamer-miRNA conjugates for targeted cancer therapy.RISC-interacting clearing 3'- 5' exoribonucleases (RICEs) degrade uridylated cleavage fragments to maintain functional RISC in Arabidopsis thaliana.Crystallin-αB regulates skeletal muscle homeostasis via modulation of argonaute2 activity.The roles of individual mammalian argonautes in RNA interference in vivo.A non-canonical site reveals the cooperative mechanisms of microRNA-mediated silencingHydrogen peroxide responsive miR153 targets Nrf2/ARE cytoprotection in paraquat induced dopaminergic neurotoxicity.Evolutionarily conserved roles of the dicer helicase domain in regulating RNA interference processing.Defining fundamental steps in the assembly of the Drosophila RNAi enzyme complex.The role of non-coding RNAs in the regulation of stem cells and progenitors in the normal mammary gland and in breast tumors.Potent degradation of neuronal miRNAs induced by highly complementary targets.Destabilization of microRNAs in human cells by 3' deadenylation mediated by PARN and CUGBP1.Functional dissection of a plant ArgonauteDegradation dynamics of microRNAs revealed by a novel pulse-chase approach.Guidelines for the optimal design of miRNA-based shRNAs.Timescales and bottlenecks in miRNA-dependent gene regulation.MicroRNAs in the Neural Retina.Differential RISC association of endogenous human microRNAs predicts their inhibitory potential.MicroRNA binding sites in the coding region of mRNAs: extending the repertoire of post-transcriptional gene regulation.Effect of the guide strand 3'-end structure on the gene-silencing potency of asymmetric siRNA.Lessons from Enzyme Kinetics Reveal Specificity Principles for RNA-Guided Nucleases in RNA Interference and CRISPR-Based Genome Editing.Small-RNA asymmetry is directly driven by mammalian Argonautes.Terminal Duplex Stability and Nucleotide Identity Differentially Control siRNA Loading and Activity in RNA InterferenceAnalysis of complementarity requirements for plant microRNA targeting using a Nicotiana benthamiana quantitative transient assay.The decapping scavenger enzyme DCS-1: a new modulator of miRNA turnover.Distinct fitness costs associated with the knockdown of RNAi pathway genes in western corn rootworm adults.Synthetic RNA-Based Immunomodulatory Gene Circuits for Cancer Immunotherapy.Structural Foundations of RNA Silencing by Argonaute.Target RNAs Strike Back on MicroRNAsStructural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1Endogenous transcripts control miRNA levels and activity in mammalian cells by target-directed miRNA degradation
P2860
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P2860
Highly complementary target RNAs promote release of guide RNAs from human Argonaute2
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article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on May 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Highly complementary target RNAs promote release of guide RNAs from human Argonaute2
@en
Highly complementary target RNAs promote release of guide RNAs from human Argonaute2.
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type
label
Highly complementary target RNAs promote release of guide RNAs from human Argonaute2
@en
Highly complementary target RNAs promote release of guide RNAs from human Argonaute2.
@nl
prefLabel
Highly complementary target RNAs promote release of guide RNAs from human Argonaute2
@en
Highly complementary target RNAs promote release of guide RNAs from human Argonaute2.
@nl
P2093
P2860
P1433
P1476
Highly complementary target RNAs promote release of guide RNAs from human Argonaute2
@en
P2093
David V Morrissey
Ian J MacRae
Lisa Young
Nabanita De
Nicole-Claudia Meisner
Pick-Wei Lau
P2860
P304
P356
10.1016/J.MOLCEL.2013.04.001
P577
2013-05-01T00:00:00Z