Dehydrogenation of the indoline-containing drug 4-chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide (indapamide) by CYP3A4: correlation with in silico predictions
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Antihypertensive drugs metabolism: an update to pharmacokinetic profiles and computational approachesTwo-dimensional NMR and all-atom molecular dynamics of cytochrome P450 CYP119 reveal hidden conformational substatesImproved cytochrome P450 3A4 molecular models accurately predict the Phe215 requirement for raloxifene dehydrogenation selectivity.Conformational dynamics of CYP3A4 demonstrate the important role of Arg212 coupled with the opening of ingress, egress and solvent channels to dehydrogenation of 4-hydroxy-tamoxifen.Reversible dysphasia and statins.Current Approaches for Investigating and Predicting Cytochrome P450 3A4-Ligand InteractionsGenetic polymorphisms of metabolic enzymes and the pharmacokinetics of indapamide in Taiwanese subjects
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Dehydrogenation of the indoline-containing drug 4-chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide (indapamide) by CYP3A4: correlation with in silico predictions
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 12 December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Dehydrogenation of the indoline-containing drug 4-chloro-N-
@nl
Dehydrogenation of the indolin ...... ion with in silico predictions
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type
label
Dehydrogenation of the indoline-containing drug 4-chloro-N-
@nl
Dehydrogenation of the indolin ...... ion with in silico predictions
@en
prefLabel
Dehydrogenation of the indoline-containing drug 4-chloro-N-
@nl
Dehydrogenation of the indolin ...... ion with in silico predictions
@en
P2093
P2860
P356
P1476
Dehydrogenation of the indolin ...... ion with in silico predictions
@en
P2093
Chad Moore
Garold S Yost
James R Halpert
Santosh Kumar
P2860
P304
P356
10.1124/DMD.108.022707
P577
2008-12-12T00:00:00Z