Effect of aciclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomised, double-blind, placebo-controlled trial
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First phase 1 double-blind, placebo-controlled, randomized rectal microbicide trial using UC781 gel with a novel index of ex vivo efficacy5th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention: summary of key research and implications for policy and practice - biomedical preventionHSV-2: in pursuit of a vaccineOral antiviral therapy for prevention of genital herpes outbreaks in immunocompetent and nonpregnant patientsGenital ulcer disease treatment for reducing sexual acquisition of HIVOral antiviral therapy for prevention of genital herpes outbreaks in immunocompetent and nonpregnant patientsImmune modulation during latent herpesvirus infectionInfectious co-factors in HIV-1 transmission herpes simplex virus type-2 and HIV-1: new insights and interventionsHIV-1 prevention for HIV-1 serodiscordant couplesBehavioral and biomedical combination strategies for HIV preventionIncident HIV during pregnancy and postpartum and risk of mother-to-child HIV transmission: a systematic review and meta-analysisIn vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicideDaily oral emtricitabine/tenofovir preexposure prophylaxis and herpes simplex virus type 2 among men who have sex with menEffect of race/ethnicity on participation in HIV vaccine trials and comparison to other trials of biomedical preventionHIV incidence rates and risk factors for urban women in Zambia: preparing for a microbicide clinical trialHIV-prevention science at a crossroads: advances in reducing sexual risk.Setting the stage: current state of affairs and major challenges.Clinical parameters essential to methodology and interpretation of mucosal responsesCondomless sex and HIV transmission among serodifferent couples: current evidence and recommendations.Effects of genital ulcer disease and herpes simplex virus type 2 on the efficacy of male circumcision for HIV prevention: Analyses from the Rakai trials.Episodic therapy for genital herpes in sub-saharan Africa: a pooled analysis from three randomized controlled trials.The diaphragm and lubricant gel for prevention of cervical sexually transmitted infections: results of a randomized controlled trialEffectiveness of cellulose sulfate vaginal gel for the prevention of HIV infection: results of a Phase III trial in Nigeria.Characteristics of HIV-1 discordant couples enrolled in a trial of HSV-2 suppression to reduce HIV-1 transmission: the partners study.Sexually transmitted infections among HIV-1-discordant couples.Population-based seroprevalence of HSV-2 and syphilis in Andhra Pradesh state of India.Clinical reactivations of herpes simplex virus type 2 infection and human immunodeficiency virus disease progression markers.New concepts in understanding genital herpes.A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2HSV usurps eukaryotic initiation factor 3 subunit M for viral protein translation: novel prevention target.The role of dendritic cells in driving genital tract inflammation and HIV transmission risk: are there opportunities to intervene?Pregnancy, contraceptive use, and HIV acquisition in HPTN 039: relevance for HIV prevention trials among African womenPrevalence, incidence and correlates of HSV-2 infection in an HIV incidence adolescent and adult cohort study in western KenyaClinical and virologic efficacy of herpes simplex virus type 2 suppression by acyclovir in a multicontinent clinical trial.Population level impact of an imperfect prophylactic vaccine for herpes simplex virus-2Addressing research priorities for prevention of HIV infection in the United StatesThe past, present, and future of HIV prevention: integrating behavioral, biomedical, and structural intervention strategies for the next generation of HIV prevention.Comparison of focus HerpesSelect and Kalon HSV-2 gG2 ELISA serological assays to detect herpes simplex virus type 2 antibodies in a South African population.Experiences in conducting multiple community-based HIV prevention trials among women in KwaZulu-Natal, South Africa.Factors associated with HIV infection in married or cohabitating couples in Kenya: results from a nationally representative study.
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P2860
Effect of aciclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomised, double-blind, placebo-controlled trial
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 2008
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Effect of aciclovir on HIV-1 a ...... lind, placebo-controlled trial
@en
Effect of aciclovir on HIV-1 a ...... ind, placebo-controlled trial.
@nl
type
label
Effect of aciclovir on HIV-1 a ...... lind, placebo-controlled trial
@en
Effect of aciclovir on HIV-1 a ...... ind, placebo-controlled trial.
@nl
prefLabel
Effect of aciclovir on HIV-1 a ...... lind, placebo-controlled trial
@en
Effect of aciclovir on HIV-1 a ...... ind, placebo-controlled trial.
@nl
P2093
P2860
P50
P921
P1433
P1476
Effect of aciclovir on HIV-1 a ...... lind, placebo-controlled trial
@en
P2093
Abner Ortiz
HPTN 039 Protocol Team
James Hughes
Jonathan Fuchs
Jorge Sanchez
Martin Casapia
Scott Rose
Sheryl Zwerski
P2860
P304
P356
10.1016/S0140-6736(08)60920-4
P407
P50
P577
2008-06-01T00:00:00Z