Mutations at embB codon 306 are an important molecular indicator of ethambutol resistance in Mycobacterium tuberculosis.
about
Evolution of drug resistance in tuberculosis: recent progress and implications for diagnosis and therapyNew insights into fluoroquinolone resistance in Mycobacterium tuberculosis: functional genetic analysis of gyrA and gyrB mutationsDiscordance across Phenotypic and Molecular Methods for Drug Susceptibility Testing of Drug-Resistant Mycobacterium tuberculosis Isolates in a Low TB Incidence CountryIntegrated microfluidic card with TaqMan probes and high-resolution melt analysis to detect tuberculosis drug resistance mutations across 10 genes.The future of molecular diagnostics for drug-resistant tuberculosis.Allelic exchange and mutant selection demonstrate that common clinical embCAB gene mutations only modestly increase resistance to ethambutol in Mycobacterium tuberculosis.Molecular detection of mutations associated with first- and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium tuberculosis.Mycobacterium tuberculosis embB codon 306 mutations confer moderately increased resistance to ethambutol in vitro and in vivo.Analysis of embCAB mutations associated with ethambutol resistance in multidrug-resistant mycobacterium tuberculosis isolates from ChinaCharacteristics of embB mutations in multidrug-resistant Mycobacterium tuberculosis isolates in Henan, ChinaMolecular Analysis of the embCAB Locus and embR Gene Involved in Ethambutol Resistance in Clinical Isolates of Mycobacterium tuberculosis in France.Detection of first- and second-line drug resistance in Mycobacterium tuberculosis clinical isolates by pyrosequencing.Old drugs, new purpose: retooling existing drugs for optimized treatment of resistant tuberculosis.Performance Assessment of the Polymerase Chain Reaction-Restriction Fragment Length Polymorphism Method for Rapid Detection of Susceptibility to Ethambutol and Molecular Prediction of Extensively Drug-resistant Tuberculosis in Clinical Isolates of MGeographic Differences in the Contribution of ubiA Mutations to High-Level Ethambutol Resistance in Mycobacterium tuberculosisThe arabinosyltransferase EmbC is inhibited by ethambutol in Mycobacterium tuberculosis.Association between embB Codon 306 Mutations, Phenotypic Resistance Profiles, and Genotypic Characterization in Clinical Mycobacterium tuberculosis Isolates from Hebei, ChinaSystematic review of allelic exchange experiments aimed at identifying mutations that confer drug resistance in Mycobacterium tuberculosis.Arabinogalactan and lipoarabinomannan biosynthesis: structure, biogenesis and their potential as drug targets.An application of competitive reporter monitored amplification (CMA) for rapid detection of single nucleotide polymorphisms (SNPs).Fighting an old disease with modern tools: characteristics and molecular detection methods of drug-resistant Mycobacterium tuberculosis.Simultaneous identification of mycobacterial isolates to the species level and determination of tuberculosis drug resistance by PCR followed by electrospray ionization mass spectrometry.Mutations Found in embCAB, embR, and ubiA Genes of Ethambutol-Sensitive and -Resistant Mycobacterium tuberculosis Clinical Isolates from China.Identification of Mycobacterium species and Mycobacterium tuberculosis complex resistance determinants by use of PCR-electrospray ionization mass spectrometry.Evolution of high-level ethambutol-resistant tuberculosis through interacting mutations in decaprenylphosphoryl-β-D-arabinose biosynthetic and utilization pathway genes.Molecular and Growth-Based Drug Susceptibility Testing of Mycobacterium tuberculosis Complex for Ethambutol Resistance in the United StatesembB306 mutations as molecular indicators to predict ethambutol susceptibility in Mycobacterium tuberculosis.Draft Genome Sequence of the First Confirmed Isolate of Multidrug-Resistant Mycobacterium tuberculosis in Tasmania.Comparative Genomic Analysis of Two Clonally Related Multidrug Resistant Mycobacterium tuberculosis by Single Molecule Real Time Sequencing.Purification and characterization of an endo-D: -arabinase produced by cellulomonas.Molecular epidemiology of tuberculosis in Tasmania and genomic characterisation of its first known multi-drug resistant case.The novel responses of ethambutol against Mycobacterium smegmatis mc²155 Revealed by proteomics analysis.embCAB sequence variation among ethambutol-resistant Mycobacterium tuberculosis isolates without embB306 mutation
P2860
Q27016579-72C3EDF4-2882-43C7-9C97-A9832975B91CQ28480855-A89B7021-FC34-44F2-BF8E-5FD685A74FA7Q28551469-05F71BEB-8B31-46F3-A3CC-BE19229218C5Q30300560-15D9164B-E648-4B00-A402-79058CF94B09Q30455525-938145F4-D480-4303-80D6-90DC1C76527DQ33559021-7359E62F-3D7A-4623-83AF-6A97FA7F4ABFQ34933405-985DCAD4-9267-49CD-B5B3-9BF31B11D1CEQ35005024-A5DBCDB9-C48B-47B3-B990-C2EF75C1D463Q35168964-FC09E481-D760-4187-B00E-F8359F25F696Q35210458-E74575A6-D71E-4F81-80FB-FD4D12099A01Q35859945-500F99EC-AA67-4EA3-835E-B6FC2FA7DE22Q36022970-612BB23D-DB74-409F-A1AF-9B7BF7A0B334Q36461593-716F17AA-C721-4018-B1BD-DCAFC585B181Q37007631-7BAF69C7-F1E2-4D9F-A856-D81B25FB76B0Q37023233-EEBB5218-165C-451A-944B-7EA8D81A673AQ37392900-4A9CA39B-F731-421D-8046-DC854D3F44BCQ37428663-82BB65E2-4ED3-4AFC-B387-C54BFDA83899Q37458296-8B1D71A7-E6FC-4F24-A551-50BB3E4ACBB6Q37970706-BEACE473-109C-40E6-ACC2-5968373BAA2EQ38368508-5C12F337-AC14-4672-A3BD-0E324EDD5ECCQ38545953-A132F6B0-322A-4BF8-992D-5F362CF099ABQ39964636-6A620BD1-9D9E-4F41-8C8E-EAC77E534FE7Q40487996-8762DF0C-611F-4DC5-B684-07DEF49A23BCQ41867988-C68681A0-869D-41C2-97E7-FB63711EF578Q42249147-40DB0B17-E7C7-40AD-9B13-A4841495CA82Q42577091-97FC69E0-2E27-40E8-B6B1-F67056419F6FQ46639370-0B5D70CE-2D74-4615-A416-344A3FB78FAAQ47109976-2D3758AE-28FE-42A2-8319-668E8E5A687BQ47113538-FB8224C5-CEB3-43EA-8736-69D8BC1404FAQ50264769-23472C83-F10C-4BF1-BF67-B4DA572B9A95Q50351099-E4BEEBA9-1DEF-4C65-97ED-9A24D959C050Q54430301-4FCDC722-8E90-4266-A147-5926FBF01417Q58485197-AC0CBDC7-FA18-45C5-AD88-FB5DA18C5C70
P2860
Mutations at embB codon 306 are an important molecular indicator of ethambutol resistance in Mycobacterium tuberculosis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 22 December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mutations at embB codon 306 ar ...... in Mycobacterium tuberculosis.
@en
Mutations at embB codon 306 ar ...... in Mycobacterium tuberculosis.
@nl
type
label
Mutations at embB codon 306 ar ...... in Mycobacterium tuberculosis.
@en
Mutations at embB codon 306 ar ...... in Mycobacterium tuberculosis.
@nl
prefLabel
Mutations at embB codon 306 ar ...... in Mycobacterium tuberculosis.
@en
Mutations at embB codon 306 ar ...... in Mycobacterium tuberculosis.
@nl
P2093
P2860
P356
P1476
Mutations at embB codon 306 ar ...... in Mycobacterium tuberculosis.
@en
P2093
Angela M Starks
Aysel Gumusboga
Bonnie B Plikaytis
James E Posey
Thomas M Shinnick
P2860
P304
P356
10.1128/AAC.01357-08
P407
P577
2008-12-22T00:00:00Z