Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus
about
Opportunities and challenges of whole-genome and -exome sequencing.Evaluation of 10 SLE susceptibility loci in Asian populations, which were initially identified in European populations.Autophagy-related gene LRRK2 is likely a susceptibility gene for systemic lupus erythematosus in northern Han Chinese.Confirmation of five novel susceptibility loci for systemic lupus erythematosus (SLE) and integrated network analysis of 82 SLE susceptibility loci.Novel risk genes for systemic lupus erythematosus predicted by random forest classificationLupus in the far east: a modern epidemic.Transancestral mapping and genetic load in systemic lupus erythematosus.Associations between PTPN22 and TLR9 polymorphisms and systemic lupus erythematosus: a comprehensive meta-analysis.The effect of ethnicity and genetic ancestry on the epidemiology, clinical features and outcome of systemic lupus erythematosus.Multiple variants in 5q31.1 are associated with systemic lupus erythematosus susceptibility and subphenotypes in the Han Chinese population.A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases.Genome-Wide Association Analysis Reveals Genetic Heterogeneity of Sjögren's Syndrome According to Ancestry.Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity.Epigenetic Variability in Systemic Lupus Erythematosus: What We Learned from Genome-Wide DNA Methylation Studies.The genetics revolution in rheumatology: large scale genomic arrays and genetic mapping.Review: Enhancers in Autoimmune Arthritis: Implications and Therapeutic Potential.Systemic lupus erythematosus: BAFF emerges from the genetic shadows.CD4+CD28+KIR+CD11ahi T cells correlate with disease activity and are characterized by a pro-inflammatory epigenetic and transcriptional profile in lupus patients.The Role of the Transcription Factor Ets1 in Lupus and Other Autoimmune Diseases.Abnormal B-cell development in Systemic Lupus Erythematosus: what the genetics tell us.Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.Updates in Lupus Genetics.DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus.Research Techniques Made Simple: Using Genome-Wide Association Studies to Understand Complex Cutaneous Disorders.A novel transcript isoform of STING that sequesters cGAMP and dominantly inhibits innate nucleic acid sensing.Meta-analysis of GWAS on both Chinese and European populations identifies GPR173 as a novel X chromosome susceptibility gene for SLE.The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE.Dysregulated heme oxygenase-1low M2-like macrophages augment lupus nephritis via Bach1 induced by type I interferons.Association of a rare variant of the TNFSF13B gene with susceptibility to Rheumatoid Arthritis and Systemic Lupus Erythematosus.Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus.Plasma Cell Differentiation Pathways in Systemic Lupus Erythematosus.Whole Exome Sequencing of Patients from Multicase Families with Systemic Lupus Erythematosus Identifies Multiple Rare Variants.Genetic contributions to lupus nephritis in a multi-ethnic cohort of systemic lupus erythematous patients.Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networksInterferon-λ3/4 genetic variants and interferon-λ3 serum levels are biomarkers of lupus nephritis and disease activity in Taiwanese
P2860
Q36278942-54B3E603-612C-4B11-B03C-8DDF656E9D42Q37609588-1D5AEFE6-DFD5-4969-AE9C-4487A75ED44EQ37706696-3C77F4AF-5415-4BF0-B9C2-316BEC9937DAQ38437890-96C51B06-A97E-4319-8F29-8A83EEEE7F5EQ38663531-DA023238-2E77-4936-9CDB-1F600F02A232Q38672989-1DCC930F-7E8D-42E3-B656-69F15DA56120Q38676110-18C1B466-E1C1-4563-B685-9C6A5EE2B3ECQ38681399-720D74F6-DF0A-41D5-95CB-F642975FEDABQ38784456-62E8969F-D1D2-4F94-A2D2-1B4C0AC5CBFAQ38987696-2A8D815B-C40A-474F-B643-705A80532310Q38991998-1527B6BF-8A14-4737-ACB2-2096D96DB92BQ39026679-E2089A58-5297-45FD-B23F-E39FF7EBB058Q39272758-DDFA98D7-D788-447D-A73E-CF3771FA598AQ39282560-71D31023-026A-4A7F-AB08-1D79DF3B51DEQ39343367-D22F8ED1-1A01-4493-B511-CC857110E892Q39407376-7C66F83B-FD1B-4A94-B752-3C088318964BQ46425793-DDE0EC05-7388-4112-BEC8-F546616F8226Q46559300-AD76BAAF-EEA4-4D56-BE87-F2F7743482EDQ47134266-CDE4D5C8-66B6-4BE2-887B-1E49973FF6D8Q47365066-AEDC3FEE-EF94-4806-AECB-240EBB9C5CADQ47602743-C4A0FDC2-5EDE-4CD5-9B5B-6FFCD5FC0380Q47852851-A698D08E-987A-4283-818E-4FFCEF49BEBEQ50044502-DAC3E139-3B1C-4344-8133-A06FC8DEFB5CQ52373466-B08CA04B-1595-4FC6-A1DB-D389ABB7392FQ52652027-58B47FA0-15F6-450A-A091-4377980AA3B4Q53283386-D061654B-5C14-40CC-9EEB-E00694210A8BQ54983754-E0F53DBF-ADC5-42AD-8943-054061A33DB8Q55027053-AC43173B-E40B-4F41-AE55-AC804F427265Q55092221-9A50D07F-D396-49DD-ADDA-059467154EC3Q55261112-DEA2FC56-87D0-4E49-A66B-EB22D26472F1Q55266542-504EF782-C242-4D76-8199-1F081F7A588DQ55449353-27DBEDF7-8BE7-438D-979B-ACC11D1197E6Q55514451-42AFA4AC-1E06-439E-82D4-932A25C53B97Q57329654-D7C49292-FFE2-400E-9E96-E0874D72BCCEQ58694999-8D0A7B2F-9E1F-4133-93D2-95F3F07C0225
P2860
Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 11 July 2016
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Genome-wide association meta-a ...... h systemic lupus erythematosus
@en
Genome-wide association meta-a ...... systemic lupus erythematosus.
@nl
type
label
Genome-wide association meta-a ...... h systemic lupus erythematosus
@en
Genome-wide association meta-a ...... systemic lupus erythematosus.
@nl
prefLabel
Genome-wide association meta-a ...... h systemic lupus erythematosus
@en
Genome-wide association meta-a ...... systemic lupus erythematosus.
@nl
P2093
P2860
P50
P356
P1433
P1476
Genome-wide association meta-a ...... h systemic lupus erythematosus
@en
P2093
Barbara G Fürnrohr
David L Morris
Deborah S Cunninghame Graham
James Bentham
Lars Rönnblom
Leilei Wen
Lingyan Chen
P2860
P2888
P304
P356
10.1038/NG.3603
P407
P577
2016-07-11T00:00:00Z