Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer. - Test2 - elhamkhani - TriplyDB

Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer.

Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer.

http://www.wikidata.org/entity/Q37146190

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Cytokine-Induced Modulation of Colorectal Cancer Role of TH17 cytokines in the control of colorectal cancer IL-17+Foxp3+ T cells: an intermediate differentiation stage between Th17 cells and regulatory T cells The role of IL-17-producing Foxp3+ CD4+ T cells in inflammatory bowel disease and colon cancer Treg functional stability and its responsiveness to the microenvironment Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan CD4+ T Cell Fate in Glomerulonephritis: A Tale of Th1, Th17, and Novel Treg Subtypes Microenvironmental regulation of tumor progression and metastasis Cellular and molecular immune profiles in renal transplant recipients after conversion from tacrolimus to sirolimus.Augmented Th17-type immune responses in preterm neonates exposed to histologic chorioamnionitis.β-Catenin promotes colitis and colon cancer through imprinting of proinflammatory properties in T cells.Differentiation of IL-17-producing effector and regulatory human T cells from lineage-committed naive precursors.Investigation of IL-23 (p19, p40) and IL-23R identifies nuclear expression of IL-23 p19 as a favorable prognostic factor in colorectal cancer: a retrospective multicenter study of 675 patients TLR4 regulates IFN-γ and IL-17 production by both thymic and induced Foxp3+ Tregs during intestinal inflammation A cellular automaton model for tumor dormancy: emergence of a proliferative switch.Current status of interleukin-10 and regulatory T-cells in cancer T helper 17 cells play a critical pathogenic role in lung cancer.Regulatory T lymphocytes are associated with less aggressive histologic features in microsatellite-unstable colorectal cancers.Adenomatous polyps are driven by microbe-instigated focal inflammation and are controlled by IL-10-producing T cells.Interplay between DNA repair and inflammation, and the link to cancer Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis.Oral interleukin-10 alleviates polyposis via neutralization of pathogenic T-regulatory cells Linking T-cell receptor sequence to functional phenotype at the single-cell level.Interleukin-21 sustains inflammatory signals that contribute to sporadic colon tumorigenesis.Regulatory T cells turn pathogenic.Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis.RORγt(+)Foxp3(+) Cells are an Independent Bifunctional Regulatory T Cell Lineage and Mediate Crescentic GN T-cell Expression of IL10 Is Essential for Tumor Immune Surveillance in the Small Intestine Enrichment of Inflammatory IL-17 and TNF-α Secreting CD4(+) T Cells within Colorectal Tumors despite the Presence of Elevated CD39(+) T Regulatory Cells and Increased Expression of the Immune Checkpoint Molecule, PD-1 IL-15-dependent balance between Foxp3 and RORγt expression impacts inflammatory bowel disease.Regulatory T cells that co-express RORγt and FOXP3 are pro-inflammatory and immunosuppressive and expand in human pancreatic cancer.Lipopolysaccharide-Induced Chorioamnionitis Promotes IL-1-Dependent Inflammatory FOXP3+ CD4+ T Cells in the Fetal Rhesus Macaque.Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis.Production of Proinflammatory Cytokines by Monocytes in Liver-Transplanted Recipients with De Novo Autoimmune Hepatitis Is Enhanced and Induces TH1-like Regulatory T Cells.Preferential expansion of pro-inflammatory Tregs in human non-small cell lung cancer Regulatory T cells with multiple suppressive and potentially pro-tumor activities accumulate in human colorectal cancer Chronic Inflammation: Synergistic Interactions of Recruiting Macrophages (TAMs) and Eosinophils (Eos) with Host Mast Cells (MCs) and Tumorigenesis in CALTs. M-CSF, Suitable Biomarker for Cancer Diagnosis!Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells.Targeting Tregs in Malignant Brain Cancer: Overcoming IDO.Microbial activation of gut dendritic cells and the control of mucosal immunity.

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Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer.

http://www.wikidata.org/entity/Q37146190

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

@tr

scientific article published on December 2012

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer.

@en

Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer.

@nl

type

label

Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer.

@en

Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer.

@nl

prefLabel

Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer.

@en

Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer.

@nl

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SCITRANSLMED.3004566

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Science Translational Medicine

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Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer.

@en

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Amy L Halverson

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Andreas Bonertz

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Anne-Marie Boller

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Ashima Singal

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Bara Sarraj

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Barry P Sandall

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David J Bentrem

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David M Mahvi

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Denise Scholtens

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Fotini Gounari

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P2860

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases

Segmented filamentous bacteria take the stage

T helper 17 cells promote cytotoxic T cell activation in tumor immunity

Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth

IL-17 and Th17 Cells

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

Isoform-specific inhibition of ROR alpha-mediated transcriptional activation by human FOXP3

An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells

IL-23 promotes tumour incidence and growth

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164ra159

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scholarly article

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10.1126/SCITRANSLMED.3004566

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P433

164

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4

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2012-12-01T00:00:00Z

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233930231

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23241743

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3762575

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