Negative elongation factor (NELF) coordinates RNA polymerase II pausing, premature termination, and chromatin remodeling to regulate HIV transcription.
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Impact of Chromatin on HIV ReplicationTranscriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cureThe Old and New Testaments of gene regulation. Evolution of multi-subunit RNA polymerases and co-evolution of eukaryote complexity with the RNAP II CTDRNAP II processivity is a limiting step for HIV-1 transcription independent of orientation to and activity of endogenous neighboring promotersMining the human complexome database identifies RBM14 as an XPO1-associated protein involved in HIV-1 Rev function.Negative elongation factor is required for the maintenance of proviral latency but does not induce promoter-proximal pausing of RNA polymerase II on the HIV long terminal repeat.Short chain fatty acids potently induce latent HIV-1 in T-cells by activating P-TEFb and multiple histone modifications.Blimp-1, an intrinsic factor that represses HIV-1 proviral transcription in memory CD4+ T cells.RNA polymerase II pausing as a context-dependent reader of the genome.A Two-Way Street: Regulatory Interplay between RNA Polymerase and Nascent RNA Structure.Quantitative proteomics by SWATH-MS reveals altered expression of nucleic acid binding and regulatory proteins in HIV-1-infected macrophages.HIV eradication: combinatorial approaches to activate latent viruses.Progress and challenges in the use of latent HIV-1 reactivating agentsIdentification of benzazole compounds that induce HIV-1 transcription.Super elongation complex promotes early HIV transcription and its function is modulated by P-TEFb.Assays for precise quantification of total (including short) and elongated HIV-1 transcripts.Dose-related liver injury of Geniposide associated with the alteration in bile acid synthesis and transportation.Architecture and RNA binding of the human negative elongation factor.Comparative Analysis of Tat-Dependent and Tat-Deficient Natural Lentiviruses.The Battle of RNA Synthesis: Virus versus Host.Multiple Inhibitory Factors Act in the Late Phase of HIV-1 Replication: a Systematic Review of the Literature.Mitochondrial Retrograde Signaling in Mammals Is Mediated by the Transcriptional Cofactor GPS2 via Direct Mitochondria-to-Nucleus Translocation--RNA Polymerase II Transcription Attenuation at the Yeast DNA Repair Gene, DEF1, Involves Sen1-Dependent and Polyadenylation Site-Dependent Termination.Nuclear RNA surveillance complexes silence HIV-1 transcription.
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P2860
Negative elongation factor (NELF) coordinates RNA polymerase II pausing, premature termination, and chromatin remodeling to regulate HIV transcription.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Negative elongation factor (NE ...... to regulate HIV transcription.
@en
Negative elongation factor (NE ...... to regulate HIV transcription.
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type
label
Negative elongation factor (NE ...... to regulate HIV transcription.
@en
Negative elongation factor (NE ...... to regulate HIV transcription.
@nl
prefLabel
Negative elongation factor (NE ...... to regulate HIV transcription.
@en
Negative elongation factor (NE ...... to regulate HIV transcription.
@nl
P2093
P2860
P356
P1476
Negative elongation factor (NE ...... to regulate HIV transcription.
@en
P2093
Anamika Missra
Andrew J Henderson
Chanhyo Lee
David S Gilmour
Gillian M Schiralli Lester
Gregory A Wasserman
Malini Natarajan
Martin Steffen
P2860
P304
25995-26003
P356
10.1074/JBC.M113.496489
P407
P577
2013-07-24T00:00:00Z