BMP4 mediates oxidative stress-induced retinal pigment epithelial cell senescence and is overexpressed in age-related macular degeneration.
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Protection of retina by αB crystallin in sodium iodate induced retinal degenerationAge-Related Macular Degeneration and Intracrine Biology: An HypothesisEbi/AP-1 suppresses pro-apoptotic genes expression and permits long-term survival of Drosophila sensory neuronsBmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degenerationWhat determines the switch between atrophic and neovascular forms of age related macular degeneration? - the role of BMP4 induced senescenceTranscriptional regulation of bone morphogenetic protein 4 by tumor necrosis factor and its relationship with age-related macular degeneration.Cell models to study regulation of cell transformation in pathologies of retinal pigment epitheliumOver-expression of BMP4 inhibits experimental choroidal neovascularization by modulating VEGF and MMP-9.Inhibition of p38 mitogen-activated protein kinase phosphorylation decrease tert-butyl hydroperoxide-induced apoptosis in human trabecular meshwork cellsBMP4 inhibits the proliferation of breast cancer cells and induces an MMP-dependent migratory phenotype in MDA-MB-231 cells in 3D environmentp53, oxidative stress, and agingMechanism of RPE cell death in α-crystallin deficient mice: a novel and critical role for MRP1-mediated GSH effluxInflammatory priming predisposes mice to age-related retinal degeneration.Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione.Proinflammatory cytokines decrease the expression of genes critical for RPE functionHumanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage.Oxidative stress-induced premature senescence dysregulates VEGF and CFH expression in retinal pigment epithelial cells: Implications for Age-related Macular Degeneration.Transient exposure to androgens induces a remarkable self-sustained quiescent state in dispersed prostate cancer cells.TGF-β Family Signaling in the Control of Cell Proliferation and Survival.Epithelial cell senescence: an adaptive response to pre-carcinogenic stresses?Senescent cells: an emerging target for diseases of ageing.Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: relevance to age-related macular degeneration.The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction.Bone morphogenetic protein 4 (BMP4) signaling in retinoblastoma cells.Dynamics of H2O2 availability to ARPE-19 cultures in models of oxidative stress.Cigarette smoke induced autophagy-impairment regulates AMD pathogenesis mechanisms in ARPE-19 cells.Alterations of retinal pigment epithelium cause AMD-like retinopathy in senescence-accelerated OXYS ratsSustained gene expression in the retina by improved episomal vectors.The Role of Kinase Modulators in Cellular Senescence for Use in Cancer Treatment.Role of sphingolipids in senescence: implication in aging and age-related diseases
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BMP4 mediates oxidative stress-induced retinal pigment epithelial cell senescence and is overexpressed in age-related macular degeneration.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 21 January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
BMP4 mediates oxidative stress ...... -related macular degeneration.
@en
BMP4 mediates oxidative stress ...... -related macular degeneration.
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type
label
BMP4 mediates oxidative stress ...... -related macular degeneration.
@en
BMP4 mediates oxidative stress ...... -related macular degeneration.
@nl
prefLabel
BMP4 mediates oxidative stress ...... -related macular degeneration.
@en
BMP4 mediates oxidative stress ...... -related macular degeneration.
@nl
P2093
P2860
P356
P1476
BMP4 mediates oxidative stress ...... -related macular degeneration.
@en
P2093
Christine Spee
Danhong Zhu
David R Hinton
Stephen J Ryan
P2860
P304
P356
10.1074/JBC.M809393200
P407
P577
2009-01-21T00:00:00Z