Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation.
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Activation of the aryl hydrocarbon receptor during pregnancy in the mouse alters mammary development through direct effects on stromal and epithelial tissuesDistinct effects of the mesenchymal dysplasia gene variant of murine Patched-1 protein on canonical and non-canonical Hedgehog signaling pathwaysActivation of Erk by sonic hedgehog independent of canonical hedgehog signalling.Epithelial and non-epithelial Ptch1 play opposing roles to regulate proliferation and morphogenesis of the mouse mammary glandHedgehog signaling in the normal and neoplastic mammary gland.A novel signaling pathway mediated by the nuclear targeting of C-terminal fragments of mammalian Patched 1Oestrogen receptor-alpha regulates non-canonical Hedgehog-signalling in the mammary gland.Methods for preparing fluorescent and neutral red-stained whole mounts of mouse mammary glandsAltered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened.Modulation of fibroblast growth factor signaling is essential for mammary epithelial morphogenesis.Targeted expression of GLI1 in the salivary glands results in an altered differentiation program and hyperplasia.Shared signaling pathways in normal and breast cancer stem cells.Immunobiology and signaling pathways of cancer stem cells: implication for cancer therapy.The Hedgehog signalling pathway in breast development, carcinogenesis and cancer therapy.Normal mammary development and function in mice with Ift88 deleted in MMTV- and K14-Cre expressing cellsPlk2 regulates mitotic spindle orientation and mammary gland development
P2860
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P2860
Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 18 March 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Ptch1 is required locally for ...... mically for ductal elongation.
@en
Ptch1 is required locally for ...... mically for ductal elongation.
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type
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Ptch1 is required locally for ...... mically for ductal elongation.
@en
Ptch1 is required locally for ...... mically for ductal elongation.
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Ptch1 is required locally for ...... mically for ductal elongation.
@en
Ptch1 is required locally for ...... mically for ductal elongation.
@nl
P2093
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P356
P1433
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Ptch1 is required locally for ...... mically for ductal elongation.
@en
P2093
Brandon J Wainwright
Hong Chang
John D Landua
Jonathan T Prigge
Michael T Lewis
Nikesha Harrington
Paul A Hamel
Ricardo C Moraes
Timothy F Lane
P2860
P304
P356
10.1242/DEV.023994
P407
P577
2009-03-18T00:00:00Z