Anti-LRP/LR specific antibody IgG1-iS18 and knock-down of LRP/LR by shRNAs rescue cells from Aβ42 induced cytotoxicity
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The 37kDa/67kDa laminin receptor acts as a receptor for Aβ42 internalization.High resolution imaging study of interactions between the 37 kDa/67 kDa laminin receptor and APP, beta-secretase and gamma-secretase in Alzheimer's disease.Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase ActivityAnti-LRP/LR-specific antibody IgG1-iS18 impedes adhesion and invasion of pancreatic cancer and neuroblastoma cellsAnti-LRP/LR specific antibodies and shRNAs impede amyloid beta shedding in Alzheimer's disease.Anti-LRP/LR specific antibody IgG1-iS18 significantly impedes adhesion and invasion in early and late stage colorectal carcinoma cells.The Transition of the 37-Kda Laminin Receptor (Rpsa) to Higher Molecular Weight Species: Sumoylation or Artifact?Looking into laminin receptor: critical discussion regarding the non-integrin 37/67-kDa laminin receptor/RPSA protein.Novel patented therapeutic approaches targeting the 37/67 kDa laminin receptor for treatment of cancer and Alzheimer's disease.LRP/LR Antibody Mediated Rescuing of Amyloid-β-Induced Cytotoxicity is Dependent on PrPc in Alzheimer's Disease.The 37/67 kDa laminin receptor (LR) inhibitor, NSC47924, affects 37/67 kDa LR cell surface localization and interaction with the cellular prion protein.LRP/LR specific antibody IgG1-iS18 impedes neurodegeneration in Alzheimer's disease mice.
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Anti-LRP/LR specific antibody IgG1-iS18 and knock-down of LRP/LR by shRNAs rescue cells from Aβ42 induced cytotoxicity
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on January 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Anti-LRP/LR specific antibody ...... from Aβ42 induced cytotoxicity
@en
Anti-LRP/LR specific antibody ...... rom Aβ42 induced cytotoxicity.
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type
label
Anti-LRP/LR specific antibody ...... from Aβ42 induced cytotoxicity
@en
Anti-LRP/LR specific antibody ...... rom Aβ42 induced cytotoxicity.
@nl
prefLabel
Anti-LRP/LR specific antibody ...... from Aβ42 induced cytotoxicity
@en
Anti-LRP/LR specific antibody ...... rom Aβ42 induced cytotoxicity.
@nl
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P2860
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Anti-LRP/LR specific antibody ...... from Aβ42 induced cytotoxicity
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Bianca Da Costa Dias
Clement Penny
Danielle Gonsalves
Katarina Jovanovic
Kiashanee Moodley
Melvyn Little
Stefan F T Weiss
Stefan Knackmuss
Uwe Reusch
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P2888
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10.1038/SREP02702
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P577
2013-01-01T00:00:00Z