EndoS2 is a unique and conserved enzyme of serotype M49 group A Streptococcus that hydrolyses N-linked glycans on IgG and α1-acid glycoprotein.
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Immune recruitment or suppression by glycan engineering of endogenous and therapeutic antibodiesDisease manifestations and pathogenic mechanisms of Group A Streptococcus.EndoE from Enterococcus faecalis hydrolyzes the glycans of the biofilm inhibiting protein lactoferrin and mediates growth.Bacterial glycosidases in pathogenesis and glycoengineering.EndoS and EndoS2 hydrolyze Fc-glycans on therapeutic antibodies with different glycoform selectivity and can be used for rapid quantification of high-mannose glycansIdentification of O-glycan Structures from Chicken Intestinal Mucins Provides Insight into Campylobactor jejuni Pathogenicity.CP40 from Corynebacterium pseudotuberculosis is an endo-β-N-acetylglucosaminidase.Genome Analysis of Streptococcus pyogenes Associated with Pharyngitis and Skin Infections.EndoSd: an IgG glycan hydrolyzing enzyme in Streptococcus dysgalactiae subspecies dysgalactiae.The ENGases: versatile biocatalysts for the production of homogeneous N-linked glycopeptides and glycoproteins.Fragments of bacterial endoglycosidase s and immunoglobulin g reveal subdomains of each that contribute to deglycosylation.Glycosynthase Mutants of Endoglycosidase S2 Show Potent Transglycosylation Activity and Remarkably Relaxed Substrate Specificity for Antibody Glycosylation Remodeling.Antibody-drug conjugates: Design and development for therapy and imaging in and beyond cancer, LabEx MAbImprove industrial workshop, July 27-28, 2017, Tours, France.Glycoengineering of antibody (Herceptin) through yeast expression and in vitro enzymatic glycosylation.One-pot enzymatic glycan remodeling of a therapeutic monoclonal antibody by endoglycosidase S (Endo-S) from Streptococcus pyogenes.
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P2860
EndoS2 is a unique and conserved enzyme of serotype M49 group A Streptococcus that hydrolyses N-linked glycans on IgG and α1-acid glycoprotein.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on October 2013
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
EndoS2 is a unique and conserv ...... IgG and α1-acid glycoprotein.
@en
EndoS2 is a unique and conserv ...... IgG and α1-acid glycoprotein.
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type
label
EndoS2 is a unique and conserv ...... IgG and α1-acid glycoprotein.
@en
EndoS2 is a unique and conserv ...... IgG and α1-acid glycoprotein.
@nl
prefLabel
EndoS2 is a unique and conserv ...... IgG and α1-acid glycoprotein.
@en
EndoS2 is a unique and conserv ...... IgG and α1-acid glycoprotein.
@nl
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P50
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EndoS2 is a unique and conserv ...... n IgG and α1-acid glycoprotein
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Andrew Hollands
Maria Allhorn
Pauline M Rudd
P2860
P304
P356
10.1042/BJ20130126
P407
P577
2013-10-01T00:00:00Z