The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression.
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Kynurenines in CNS disease: regulation by inflammatory cytokinesKynurenine 3-Monooxygenase: An Influential Mediator of NeuropathologyBehavioral disturbances in adult mice following neonatal virus infection or kynurenine treatment--role of brain kynurenic acid.Stress-induced increase in kynurenic acid as a potential biomarker for patients with schizophrenia and distress intoleranceAdvanced literature analysis in a Big Data world.Neuroprotective kynurenine metabolite indices are abnormally reduced and positively associated with hippocampal and amygdalar volume in bipolar disorder.Influence of kynurenine 3-monooxygenase (KMO) gene polymorphism on cognitive function in schizophreniaIncreased breakdown of kynurenine towards its neurotoxic branch in bipolar disorderA genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder.Perturbational Profiling of Metabolites in Patient Fibroblasts Implicates α-Aminoadipate as a Potential Biomarker for Bipolar Disorder.Bipolar disorder: role of immune-inflammatory cytokines, oxidative and nitrosative stress and tryptophan catabolites.Changes in kynurenine pathway metabolism in Parkinson patients with L-DOPA-induced dyskinesia.Major developments in the design of inhibitors along the kynurenine pathway.The kynurenine pathway and the brain: Challenges, controversies and promises.Role of Kynurenine Metabolism Pathway Activation in Major Depressive Disorders.Experimental drugs for bipolar psychosis.Kynurenic Acid in Schizophrenia: A Systematic Review and Meta-analysis.Repeated LPS Injection Induces Distinct Changes in the Kynurenine Pathway in Mice.Polymorphism of Kynurenine Pathway-Related Genes, Kynurenic Acid, and Psychopathological Symptoms in HIV.Serum kynurenic acid is reduced in affective psychosis.Distress intolerance, kynurenic acid, and schizophrenia.Imbalanced kynurenine pathway in schizophrenia.The Genetic Link between Parkinson's Disease and the Kynurenine Pathway Is Still Missing.Adaptive and Behavioral Changes in Kynurenine 3-Monooxygenase Knockout Mice: Relevance to Psychotic Disorders.Tulsa 1000: a naturalistic study protocol for multilevel assessment and outcome prediction in a large psychiatric sample.Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain.Tryptophan Metabolism Along the Kynurenine Pathway Downstream of Toll-like Receptor Stimulation in Peripheral Monocytes.
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P2860
The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 05 March 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The KMO allele encoding Arg452 ...... el and reduced KMO expression.
@en
The KMO allele encoding Arg452 ...... el and reduced KMO expression.
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type
label
The KMO allele encoding Arg452 ...... el and reduced KMO expression.
@en
The KMO allele encoding Arg452 ...... el and reduced KMO expression.
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prefLabel
The KMO allele encoding Arg452 ...... el and reduced KMO expression.
@en
The KMO allele encoding Arg452 ...... el and reduced KMO expression.
@nl
P2093
P2860
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The KMO allele encoding Arg452 ...... el and reduced KMO expression.
@en
P2093
C Sellgren
L Träskman-Bendz
M P Vawter
M Schalling
P2860
P2888
P304
P356
10.1038/MP.2013.11
P407
P577
2013-03-05T00:00:00Z