Connexin43 potentiates osteoblast responsiveness to fibroblast growth factor 2 via a protein kinase C-delta/Runx2-dependent mechanism - Test2 - elhamkhani - TriplyDB

Connexin43 potentiates osteoblast responsiveness to fibroblast growth factor 2 via a protein kinase C-delta/Runx2-dependent mechanism

Connexin43 potentiates osteoblast responsiveness to fibroblast growth factor 2 via a protein kinase C-delta/Runx2-dependent mechanism

http://www.wikidata.org/entity/Q37207720

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Bidirectional communication between oocytes and follicle cells: ensuring oocyte developmental competence Gap junctional regulation of signal transduction in bone cells Interaction of connexin43 and protein kinase C-delta during FGF2 signaling Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling Interleukin-1beta increases gap junctional communication among synovial fibroblasts via the extracellular-signal-regulated kinase pathway.Induction of an osteocyte-like phenotype by fibroblast growth factor-2.The osteogenic or adipogenic lineage commitment of human mesenchymal stem cells is determined by protein kinase C delta Loss of protein kinase C-δ protects against LPS-induced osteolysis owing to an intrinsic defect in osteoclastic bone resorption Identification of shoulder osteoarthritis biomarkers: comparison between shoulders with and without osteoarthritis.The transcriptional activity of osterix requires the recruitment of Sp1 to the osteocalcin proximal promoter.Thyroid-stimulating hormone induces a Wnt-dependent, feed-forward loop for osteoblastogenesis in embryonic stem cell cultures Connexin43 enhances the expression of osteoarthritis-associated genes in synovial fibroblasts in culture.Connexins and pannexins in the skeleton: gap junctions, hemichannels and more ERK acts in parallel to PKCδ to mediate the connexin43-dependent potentiation of Runx2 activity by FGF2 in MC3T3 osteoblasts.Gap junctions and hemichannels in signal transmission, function and development of bone Defective cancellous bone structure and abnormal response to PTH in cortical bone of mice lacking Cx43 cytoplasmic C-terminus domain.Beyond gap junctions: Connexin43 and bone cell signaling Connexins in the skeleton The regulation of runt-related transcription factor 2 by fibroblast growth factor-2 and connexin43 requires the inositol polyphosphate/protein kinase Cδ cascade Connexin43 modulates post-natal cortical bone modeling and mechano-responsiveness.Inhibition of connexin 43 prevents trauma-induced heterotopic ossification.An intact connexin43 is required to enhance signaling and gene expression in osteoblast-like cells.Modulation of gap junction channels and hemichannels by growth factors.Determining how defects in connexin43 cause skeletal disease.Molecular mechanisms of osteoblast/osteocyte regulation by connexin43.Shifting paradigms on the role of connexin43 in the skeletal response to mechanical load.Communication of cAMP by connexin43 gap junctions regulates osteoblast signaling and gene expression Connexin43 and the Intercellular Signaling Network Regulating Skeletal Remodeling.Defective signaling, osteoblastogenesis and bone remodeling in a mouse model of connexin 43 C-terminal truncation.Deficiency of the intermediate filament synemin reduces bone mass in vivo.Cell-printing and transfer technology applications for bone defects in mice.A Functional Assay to Assess Connexin 43-Mediated Cell-to-Cell Communication of Second Messengers in Cultured Bone Cells.Glucocorticoid Suppresses Connexin 43 Expression by Inhibiting the Akt/mTOR Signaling Pathway in Osteoblasts.Joint diseases: from connexins to gap junctions.Connexin43 intercellular communication drives the early differentiation of human bone marrow stromal cells into osteoblasts.Covalent Incorporation of Heparin Improves Chondrogenesis in Photocurable Gelatin-Methacryloyl Hydrogels.Connexin43 and Runx2 Interact to Affect Cortical Bone Geometry, Skeletal Development, and Osteoblast and Osteoclast Function.Connexin 43 and ERK regulate tension-induced signal transduction in human periodontal ligament fibroblasts.

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P2860

Connexin43 potentiates osteoblast responsiveness to fibroblast growth factor 2 via a protein kinase C-delta/Runx2-dependent mechanism

http://www.wikidata.org/entity/Q37207720

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on April 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Connexin43 potentiates osteobl ...... elta/Runx2-dependent mechanism

@en

Connexin43 potentiates osteobl ...... lta/Runx2-dependent mechanism.

@nl

type

label

Connexin43 potentiates osteobl ...... elta/Runx2-dependent mechanism

@en

Connexin43 potentiates osteobl ...... lta/Runx2-dependent mechanism.

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prefLabel

Connexin43 potentiates osteobl ...... elta/Runx2-dependent mechanism

@en

Connexin43 potentiates osteobl ...... lta/Runx2-dependent mechanism.

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MBC.E08-10-1079

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Molecular Biology of the Cell

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Connexin43 potentiates osteobl ...... elta/Runx2-dependent mechanism

@en

P2093

Carla Hebert

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Corinne Niger

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Florence Lima

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Joseph P Stains

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P2860

Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex

A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1

Connexin43: a protein from rat heart homologous to a gap junction protein from liver

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

Connexin family of gap junction proteins

Msx-2/Hox 8.1: a transcriptional regulator of the rat osteocalcin promoter

The protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2

Protein kinase C delta (PKC delta): activation mechanisms and functions

Osteocalcin and matrix Gla protein: vitamin K-dependent proteins in bone

Transduction of cell survival signals by connexin-43 hemichannels.

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2697-2708

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scholarly article

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10.1091/MBC.E08-10-1079

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11

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20

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2009-04-01T00:00:00Z

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19339281

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2688549

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