Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3
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San-Huang-Xie-Xin-Tang Constituents Exert Drug-Drug Interaction of Mutual Reinforcement at Both Pharmacodynamics and Pharmacokinetic Level: A ReviewTrisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling PathwayInhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo.Capsazepine inhibits JAK/STAT3 signaling, tumor growth, and cell survival in prostate cancerAlteration of SHP-1/p-STAT3 Signaling: A Potential Target for Anticancer Therapy.PPemd26, an anthraquinone derivative, suppresses angiogenesis via inhibiting VEGFR2 signalling.Down-regulation of STAT3 expression using vector-based RNA interference promotes apoptosis in Hepatocarcinoma cells.Resveratrol attenuates constitutive STAT3 and STAT5 activation through induction of PTPε and SHP-2 tyrosine phosphatases and potentiates sorafenib-induced apoptosis in renal cell carcinoma.Emodin potentiates the antiproliferative effect of interferon α/β by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasomeEmodin ameliorates bleomycin-induced pulmonary fibrosis in rats by suppressing epithelial-mesenchymal transition and fibroblast activation.Activation of AMPKα mediates additive effects of solamargine and metformin on suppressing MUC1 expression in castration-resistant prostate cancer cellsEmodin inhibits migration and invasion of MHCC-97H human hepatocellular carcinoma cells.Madagascine Induces Vasodilatation via Activation of AMPK.Twist in hepatocellular carcinoma: pathophysiology and therapeutics.Ginkgolic Acid C 17:1, Derived from Ginkgo biloba Leaves, Suppresses Constitutive and Inducible STAT3 Activation through Induction of PTEN and SHP-1 Tyrosine Phosphatase.Implication of protein tyrosine phosphatase SHP-1 in cancer-related signaling pathways.Emodin and Its Role in Chronic Diseases.Personalization of cancer treatment using predictive simulationAscochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3.STAT3 regulates glycolysis via targeting hexokinase 2 in hepatocellular carcinoma cells.Emodin prevents intima thickness via Wnt4/Dvl-1/β-catenin signaling pathway mediated by miR-126 in balloon-injured carotid artery ratsTheaflavins suppress tumor growth and metastasis via the blockage of the STAT3 pathway in hepatocellular carcinoma.Inhibition of 32Dp210 cells harboring T315I mutation by a novel derivative of emodin correlates with down-regulation of BCR-ABL and its downstream signaling pathways.An indel polymorphism in the 3' untranslated region of JAK1 confers risk for hepatocellular carcinoma possibly by regulating JAK1 transcriptional activity in a Chinese population.Drug Delivery System for Emodin Based on Mesoporous Silica SBA-15.The Roles of Protein Tyrosine Phosphatases in Hepatocellular Carcinoma.The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies
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Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Emodin inhibits growth and ind ...... y blocking activation of STAT3
@en
Emodin inhibits growth and ind ...... blocking activation of STAT3.
@nl
type
label
Emodin inhibits growth and ind ...... y blocking activation of STAT3
@en
Emodin inhibits growth and ind ...... blocking activation of STAT3.
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prefLabel
Emodin inhibits growth and ind ...... y blocking activation of STAT3
@en
Emodin inhibits growth and ind ...... blocking activation of STAT3.
@nl
P2093
P2860
P356
P1476
Emodin inhibits growth and ind ...... y blocking activation of STAT3
@en
P2093
Alan Prem Kumar
Aruljothi Subramaniam
Ekambaram Perumal
Kwang Seok Ahn
Muthu K Shanmugam
Shireen Vali
Shweta Kapoor
Taher Abbasi
P2860
P304
P356
10.1111/BPH.12302
P407
P577
2013-10-01T00:00:00Z