Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation. - Test2 - elhamkhani - TriplyDB

Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation.

Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation.

http://www.wikidata.org/entity/Q37238480

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Human liver mitochondrial cytochrome P450 2D6--individual variations and implications in drug metabolism Killing Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer's Disease Mechanisms of mitochondrial targeting of cytochrome P450 2E1: physiopathological role in liver injury and obesity Nucleoside diphosphate kinase of Saccharomyces cerevisiae, Ynk1p: localization to the mitochondrial intermembrane space.Mitochondrial targeting of mouse NQO1 and CYP1B1 proteins Ethanol increases mitochondrial cytochrome P450 2E1 in mouse liver and rat hepatocytes Dual targeting of antioxidant and metabolic enzymes to the mitochondrion and the apicoplast of Toxoplasma gondii Biogenesis of the preprotein translocase of the outer mitochondrial membrane: protein kinase A phosphorylates the precursor of Tom40 and impairs its import.Domain organization of long signal peptides of single-pass integral membrane proteins reveals multiple functional capacity.Trafficking of UL37 proteins into mitochondrion-associated membranes during permissive human cytomegalovirus infection.Mitochondria-targeted cytochrome P450 2E1 induces oxidative damage and augments alcohol-mediated oxidative stress.Multisite phosphorylation of human liver cytochrome P450 3A4 enhances Its gp78- and CHIP-mediated ubiquitination: a pivotal role of its Ser-478 residue in the gp78-catalyzed reaction.Bimodal targeting of microsomal cytochrome P450s to mitochondria: implications in drug metabolism and toxicity Targeting of splice variants of human cytochrome P450 2C8 (CYP2C8) to mitochondria and their role in arachidonic acid metabolism and respiratory dysfunction.Betanodavirus B2 causes ATP depletion-induced cell death via mitochondrial targeting and complex II inhibition in vitro and in vivo.Compartment-restricted biotinylation reveals novel features of prion protein metabolism in vivo.Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system.A histidine-rich motif mediates mitochondrial localization of ZnT2 to modulate mitochondrial function Bimodal targeting of cytochrome P450s to endoplasmic reticulum and mitochondria: the concept of chimeric signals.Protein folding as a driving force for dual protein targeting in eukaryotes Single translation--dual destination: mechanisms of dual protein targeting in eukaryotes.Prediction of liver injury induced by chemicals in human with a multiparametric assay on isolated mouse liver mitochondria.Subcellular localization of rat CYP2E1 impacts metabolic efficiency toward common substrates.Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells.The Localization of Cytochrome P450s CYP1A1 and CYP1A2 into Different Lipid Microdomains Is Governed by Their N-terminal and Internal Protein Regions.Mitochondrial and secretory human cytomegalovirus UL37 proteins traffic into mitochondrion-associated membranes of human cells CYP2E1 and oxidative liver injury by alcohol.Unusual properties of the cytochrome P450 superfamily.N-terminal phosphorylation of protein phosphatase 2A/Bβ2 regulates translocation to mitochondria, dynamin-related protein 1 dephosphorylation, and neuronal survival.Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain.Human cytochrome P450 2E1 mutations that alter mitochondrial targeting efficiency and susceptibility to ethanol-induced toxicity in cellular models.Amyloid precursor protein and mitochondrial dysfunction in Alzheimer's disease.Influence of protein-protein interactions on the cellular localization of cytochrome P450.Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3.Bimodal protein targeting through activation of cryptic mitochondrial targeting signals by an inducible cytosolic endoprotease.Redox signaling and protein phosphorylation in mitochondria: progress and prospects.Mitochondrial translocation of amyloid precursor protein and its cleaved products: relevance to mitochondrial dysfunction in Alzheimer's disease.Mitochondrial trafficking of APP and alpha synuclein: Relevance to mitochondrial dysfunction in Alzheimer's and Parkinson's diseases.Mitochondrial accumulation of APP and Abeta: significance for Alzheimer disease pathogenesis.

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Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation.

http://www.wikidata.org/entity/Q37238480

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 20 August 2002

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

@cs

name

Bimodal targeting of microsoma ...... cAMP-mediated phosphorylation.

@en

Bimodal targeting of microsoma ...... cAMP-mediated phosphorylation.

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type

label

Bimodal targeting of microsoma ...... cAMP-mediated phosphorylation.

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Bimodal targeting of microsoma ...... cAMP-mediated phosphorylation.

@nl

prefLabel

Bimodal targeting of microsoma ...... cAMP-mediated phosphorylation.

@en

Bimodal targeting of microsoma ...... cAMP-mediated phosphorylation.

@nl

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Journal of Biological Chemistry

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Bimodal targeting of microsoma ...... cAMP-mediated phosphorylation.

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P2093

Debkumar Pain

http://www.w3.org/2001/XMLSchema#string

Donna M Gordon

http://www.w3.org/2001/XMLSchema#string

Gopa Biswas

http://www.w3.org/2001/XMLSchema#string

Hindupur K Anandatheerthavarada

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Marie-Anne Robin

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Narayan G Avadhani

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Naresh Babu V Sepuri

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P2860

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

Elongation arrest is a physiologically important function of signal recognition particle.

Mitochondrial Hsp70/MIM44 complex facilitates protein import.

Tom40 forms the hydrophilic channel of the mitochondrial import pore for preproteins [see comment].

Mitochondrial and cytosolic isoforms of yeast fumarase are derivatives of a single translation product and have identical amino termini.

The Sec61 complex is located in both the ER and the ER-Golgi intermediate compartment

Mitochondria-to-nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion

Self-association and precursor protein binding of Saccharomyces cerevisiae Tom40p, the core component of the protein translocation channel of the mitochondrial outer membrane

Mitochondrial targeted cytochrome P450 2E1 (P450 MT5) contains an intact N terminus and requires mitochondrial specific electron transfer proteins for activity

P304

40583-40593

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scholarly article

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10.1074/JBC.M203292200

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P407

P433

43

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P478

277

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P577

2002-08-20T00:00:00Z

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P5875

11196136

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P698

12191992

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phosphorylation

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3800117

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