OX40 signaling favors the induction of T(H)9 cells and airway inflammation - Test2 - elhamkhani - TriplyDB

OX40 signaling favors the induction of T(H)9 cells and airway inflammation

OX40 signaling favors the induction of T(H)9 cells and airway inflammation

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Breaking Free of Control: How Conventional T Cells Overcome Regulatory T Cell Suppression.The TNF-family cytokine TL1A: from lymphocyte costimulator to disease co-conspirator Role of Tumor Necrosis Factor Superfamily in Neuroinflammation and Autoimmunity New insights into T cells and their signature cytokines in atopic dermatitis Molecular mechanisms of T cell co-stimulation and co-inhibition The development and in vivo function of T helper 9 cells TCR signaling to NF-κB and mTORC1: Expanding roles of the CARMA1 complex Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses Nitric oxide enhances Th9 cell differentiation and airway inflammation.Transcriptional and epigenetic regulation of T-helper lineage specification.Small-molecule modulators of the OX40-OX40 ligand co-stimulatory protein-protein interaction Cell-intrinsic role for NF-kappa B-inducing kinase in peripheral maintenance but not thymic development of Foxp3+ regulatory T cells in mice.Basophil-associated OX40 ligand participates in the initiation of Th2 responses during airway inflammation p-STAT6, PU.1, and NF-κB are involved in allergen-induced late-phase airway inflammation in asthma patients.GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response Dendritic cell expression of the signaling molecule TRAF6 is required for immune tolerance in the lung.Dendritic cells require NIK for CD40-dependent cross-priming of CD8+ T cells Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4 TRAF molecules in cell signaling and in human diseases BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis.The Costimulatory Receptor OX40 Inhibits Interleukin-17 Expression through Activation of Repressive Chromatin Remodeling Pathways Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells IL-9 and Th9 cells: progress and challenges A cell-intrinsic requirement for NF-κB-inducing kinase in CD4 and CD8 T cell memory.A mast cell-ILC2-Th9 pathway promotes lung inflammation in cystic fibrosis.TH9 cell differentiation, transcriptional control and function in inflammation, autoimmune diseases and cancer.Th9 cells: differentiation and disease.NF-κB: roles and regulation in different CD4(+) T-cell subsets.The TNFRs OX40, 4-1BB, and CD40 as targets for cancer immunotherapy.Targeting co-stimulatory pathways: transplantation and autoimmunity.The TNF family in T cell differentiation and function--unanswered questions and future directions.Helper T-cell differentiation in graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.The importance of co-stimulation in the orchestration of T helper cell differentiation.Tumor necrosis factor receptor- associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system.OX40, OX40L and Autoimmunity: a Comprehensive Review.Harnessing co-stimulatory TNF receptors for cancer immunotherapy: Current approaches and future opportunities.TNFR-Associated Factors 2 and 5 Differentially Regulate the Instructive IL-6 Receptor Signaling Required for Th17 Development.The transcription factor network in Th9 cells.Th9 cells in the pathogenesis of EAE and multiple sclerosis.

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OX40 signaling favors the induction of T(H)9 cells and airway inflammation

http://www.wikidata.org/entity/Q37249618

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 29 July 2012

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

OX40 signaling favors the induction of T

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OX40 signaling favors the induction of T(H)9 cells and airway inflammation

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type

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OX40 signaling favors the induction of T

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OX40 signaling favors the induction of T(H)9 cells and airway inflammation

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OX40 signaling favors the induction of TH9 cells and airway inflammation

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OX40 signaling favors the induction of T

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OX40 signaling favors the induction of T(H)9 cells and airway inflammation

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Nature Immunology

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OX40 signaling favors the induction of T(H)9 cells and airway inflammation

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Elizabeth J Taparowsky

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Haibin Wang

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Matthew C Walsh

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Savithri Balasubramanian

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Wentao Liu

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Xiufeng Chu

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Yongwon Choi

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P2860

Coordination between NF-kappaB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues

Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

TNF/TNFR family members in costimulation of T cell responses

Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40)

OX40/OX40L costimulation affects induction of Foxp3+ regulatory T cells in part by expanding memory T cells in vivo

IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

Regulation and function of NF-kappaB transcription factors in the immune system

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981-990

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scholarly article

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10.1038/NI.2390

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10

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2012-07-29T00:00:00Z

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230581745

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22842344

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3806044

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