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Endocytotic Routes of Cobra Cardiotoxins Depend on Spatial Distribution of Positively Charged and Hydrophobic Domains to Target Distinct Types of Sulfated Glycoconjugates on Cell SurfaceA highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagyInteractions of the proteins of neuronal ceroid lipofuscinosis: clues to functionCoxiella burnetii phase I and II variants replicate with similar kinetics in degradative phagolysosome-like compartments of human macrophagesRole of AP1 and Gadkin in the traffic of secretory endo-lysosomes.A new class of carriers that transport selective cargo from the trans Golgi network to the cell surface.Actin remodeling by ADF/cofilin is required for cargo sorting at the trans-Golgi network.Quantitative proteomic analysis of gastric cancer tissue reveals novel proteins in platelet-derived growth factor b signaling pathwayPhagocytosis of retinal rod and cone photoreceptors.Rag GTPases are cardioprotective by regulating lysosomal function.Differential requirement for cathepsin D for processing of the full length and C-terminal fragment of the malaria antigen MSP1.An aspartyl cathepsin, CTH3, is essential for proprotein processing during secretory granule maturation in Tetrahymena thermophila.Class IA phosphatidylinositol 3-kinase p110α regulates phagosome maturation.Cathepsin D: Regulation in mammary gland remodeling, misregulation in breast cancerCathepsin inhibition-induced lysosomal dysfunction enhances pancreatic beta-cell apoptosis in high glucoseAlpha-synuclein interacts with Glucocerebrosidase providing a molecular link between Parkinson and Gaucher diseasesα-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2.Characterisation and expression analysis of cathepsins and ubiquitin-proteasome genes in gilthead sea bream (Sparus aurata) skeletal muscle.Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disordersThe Role of Oxidized Cholesterol in Diabetes-Induced Lysosomal Dysfunction in the Brain.Proteomic responses to elevated ocean temperature in ovaries of the ascidian Ciona intestinalis.The 5-phosphatase OCRL mediates retrograde transport of the mannose 6-phosphate receptor by regulating a Rac1-cofilin signalling module.Gallium nanoparticles facilitate phagosome maturation and inhibit growth of virulent Mycobacterium tuberculosis in macrophages.Evidence for lysosomal exocytosis and release of aggrecan-degrading hydrolases from hypertrophic chondrocytes, in vitro and in vivo.Altered endosome biogenesis in prostate cancer has biomarker potential.Regulation of protein glycosylation and sorting by the Golgi matrix proteins GRASP55/65.Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenanceAbelson tyrosine kinase controls phagosomal acidification required for killing of Mycobacterium tuberculosis in human macrophagesCathepsins mediate tumor metastasis.Loss of melanoregulin (MREG) enhances cathepsin-D secretion by the retinal pigment epitheliumMolecular Imaging of Proteases in Cancer.Update of the mutation spectrum and clinical correlations of over 360 mutations in eight genes that underlie the neuronal ceroid lipofuscinoses.Two Faces of Cathepsin D: Physiological Guardian Angel and Pathological Demon.The Role of Cathepsin D in the Pathogenesis of Human Neurodegenerative Disorders.Exploring the role of microglia in cortical spreading depression in neurological disease.Prostate cell lines as models for biomarker discovery: performance of current markers and the search for new biomarkers.Proteomic profiling of N-linked glycoproteins identifies ConA-binding procathepsin D as a novel serum biomarker for hepatocellular carcinoma.E3 ubiquitin ligase NKLAM is a macrophage phagosome protein and plays a role in bacterial killing.A role for presenilins in autophagy revisited: normal acidification of lysosomes in cells lacking PSEN1 and PSEN2.PCSK9-mediated degradation of the LDL receptor generates a 17 kDa C-terminal LDL receptor fragment.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 30 August 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Cathepsin D: a cellular roadmap.
@en
Cathepsin D: a cellular roadmap.
@nl
type
label
Cathepsin D: a cellular roadmap.
@en
Cathepsin D: a cellular roadmap.
@nl
prefLabel
Cathepsin D: a cellular roadmap.
@en
Cathepsin D: a cellular roadmap.
@nl
P2093
P1476
Cathepsin D: a cellular roadmap.
@en
P2093
Andreas Maurer
Hubert Kalbacher
Nousheen Zaidi
Sebastian Nieke
P356
10.1016/J.BBRC.2008.08.099
P407
P577
2008-08-30T00:00:00Z