Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects - Test2 - elhamkhani - TriplyDB

Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects

Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects

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The Therapeutic Potential of the Ketogenic Diet in Treating Progressive Multiple Sclerosis Role of β-hydroxybutyrate, its polymer poly-β-hydroxybutyrate and inorganic polyphosphate in mammalian health and disease Ketone ester effects on metabolism and transcription.The collective therapeutic potential of cerebral ketone metabolism in traumatic brain injury A new way to produce hyperketonemia: use of ketone ester in a case of Alzheimer's disease Non-Toxic Metabolic Management of Metastatic Cancer in VM Mice: Novel Combination of Ketogenic Diet, Ketone Supplementation, and Hyperbaric Oxygen Therapy.Ketone Bodies and Exercise Performance: The Next Magic Bullet or Merely Hype?An In Silico Knockout Model for Gastrointestinal Absorption Using a Systems Pharmacology Approach - Development and Application for Ketones.Ketogenic diet sensitizes glucose control of hippocampal excitability.Ketone body therapy: from the ketogenic diet to the oral administration of ketone ester.β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares.Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in Sprague-Dawley rats.Ketone body metabolism and cardiovascular disease Can Ketones Help Rescue Brain Fuel Supply in Later Life? Implications for Cognitive Health during Aging and the Treatment of Alzheimer's Disease Novel ketone diet enhances physical and cognitive performance Exogenous Ketone Supplements Reduce Anxiety-Related Behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk Rats.A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome.The Population Pharmacokinetics of D-β-hydroxybutyrate Following Administration of (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate.Cancer as a metabolic disease: implications for novel therapeutics.Acute nutritional ketosis: implications for exercise performance and metabolism.Do ketogenic diets really suppress appetite? A systematic review and meta-analysis.Effects of ketone bodies in Alzheimer's disease in relation to neural hypometabolism, β-amyloid toxicity, and astrocyte function.Can ketones compensate for deteriorating brain glucose uptake during aging? Implications for the risk and treatment of Alzheimer's disease.β-Hydroxybutyrate in the Brain: One Molecule, Multiple Mechanisms.Metabolism of ketone bodies during exercise and training: physiological basis for exogenous supplementation.Multi-dimensional Roles of Ketone Bodies in Fuel Metabolism, Signaling, and Therapeutics.Strategies to Improve Adherence to Dietary Weight Loss Interventions in Research and Real-World Settings.A Ketone Ester Drink Increases Postexercise Muscle Glycogen Synthesis in Humans Intake of a Ketone Ester Drink during Recovery from Exercise Promotes mTORC1 Signaling but Not Glycogen Resynthesis in Human Muscle (R)-3-oxobutyl 3-hydroxybutanoate (OBHB) induces hyperketonemiain Alzheimer's disease Ketone strong: emerging evidence for a therapeutic role of ketone bodies in neurological and neurodegenerative diseases.Metabolic regulation of NLRP3.The therapeutic potential of a calorie-restricted ketogenic diet for the management of Leber hereditary optic neuropathy.Ketone Diester Ingestion Impairs Time-Trial Performance in Professional Cyclists.On the Metabolism of Exogenous Ketones in Humans.Effect of acute ingestion of β-hydroxybutyrate salts on the response to graded exercise in trained cyclists.Booster Ketones: Battling Hunger.Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease.A Ketone Ester Drink Lowers Human Ghrelin and Appetite.How Can a Ketogenic Diet Improve Motor Function?

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Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects

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scientific article published on 03 May 2012

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Kinetics, safety and tolerabil ...... rate in healthy adult subjects

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J.YRTPH.2012.04.008

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Regulatory Toxicology and Pharmacology

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Kinetics, safety and tolerabil ...... rate in healthy adult subjects

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Ashley Roberts

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Emma Carter

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Jeremy Robertson

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Kathy Musa-Veloso

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Kieran Clarke

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Kirill Tchabanenko

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M Todd King

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Manki Ho

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Richard L Veech

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Robert Pawlosky

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Metabolic effects of the very-low-carbohydrate diets: misunderstood "villains" of human metabolism

Brain metabolism during fasting

Control of glucose utilization in working perfused rat heart

Ketone bodies: a review of physiology, pathophysiology and application of monitoring to diabetes.

Ketone bodies, potential therapeutic uses.

Ketoacids? Good medicine?

The risk and outcome of cerebral oedema developing during diabetic ketoacidosis

Ketones: metabolism's ugly duckling.

The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism.

Fuel metabolism in starvation.

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401-408

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scholarly article

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10.1016/J.YRTPH.2012.04.008

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2012-05-03T00:00:00Z

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224913833

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22561291

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3810007

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