Apical sorting of a voltage- and Ca2+-activated K+ channel alpha -subunit in Madin-Darby canine kidney cells is independent of N-glycosylation
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The ducky(2J) mutation in Cacna2d2 results in reduced spontaneous Purkinje cell activity and altered gene expressionReciprocal modulation between the alpha and beta 4 subunits of hSlo calcium-dependent potassium channelsBiotin-responsive basal ganglia disease-linked mutations inhibit thiamine transport via hTHTR2: biotin is not a substrate for hTHTR2Role of lipid rafts in membrane delivery of renal epithelial Na+-K+-ATPase, thick ascending limbMiRP3 acts as an accessory subunit with the BK potassium channelThe beta1 subunit of Na+/K+-ATPase interacts with BKCa channels and affects their steady-state expression on the cell surfaceRaft composition at physiological temperature and pH in the absence of detergents.Functional insights into modulation of BKCa channel activity to alter myometrial contractility.Cholesterol depletion alters amplitude and pharmacology of vascular calcium-activated chloride channelsAcute alcohol tolerance is intrinsic to the BKCa protein, but is modulated by the lipid environment.Gramicidin A channels switch between stretch activation and stretch inactivation depending on bilayer thicknessRegulation of potassium channel trafficking in the distal nephron.Bilayer thickness modulates the conductance of the BK channel in model membranes.Sphingolipid trafficking and protein sorting in epithelial cells.Liposome reconstitution and modulation of recombinant N-methyl-D-aspartate receptor channels by membrane stretch.Large conductance, calcium- and voltage-gated potassium (BK) channels: regulation by cholesterol.Antiribosomal-P autoantibodies from psychiatric lupus target a novel neuronal surface protein causing calcium influx and apoptosis.Role of N- and O-glycans in polarized biosynthetic sorting.Stiffened lipid platforms at molecular force foci.Immunolocalization of the Ca2+-activated K+ channel Slo1 in axons and nerve terminals of mammalian brain and cultured neuronsPolarized traffic of LRP1 involves AP1B and SNX17 operating on Y-dependent sorting motifs in different pathways.Cholesterol depletion induces PKA-mediated basolateral-to-apical transcytosis of the scavenger receptor class B type I in MDCK cells.The role of cell cholesterol and the cytoskeleton in the interaction between IK1 and maxi-K channels.Molecular mechanisms of BK channel activation.Clathrin and AP1B: key roles in basolateral trafficking through trans-endosomal routesCholesterol and ion channels.Regulation of ion channels by membrane lipids.N-Glycosylation instead of cholesterol mediates oligomerization and apical sorting of GPI-APs in FRT cellsSelective mobility and sensitivity to SNAREs is exhibited by the Arabidopsis KAT1 K+ channel at the plasma membrane.Novel mechanism for regulation of epidermal growth factor receptor endocytosis revealed by protein kinase A inhibition.Slo1 caveolin-binding motif, a mechanism of caveolin-1-Slo1 interaction regulating Slo1 surface expression.Sorting competition with membrane-permeable peptides in intact epithelial cells revealed discrimination of transmembrane proteins not only at the trans-Golgi network but also at pre-Golgi stages.Inhibitors of glycosphingolipid biosynthesis reduce transepithelial electrical resistance in MDCK I and FRT cells.Calcium activation of BK(Ca) potassium channels lacking the calcium bowl and RCK domains.The cytoplasmic tail of large conductance, voltage- and Ca2+-activated K+ (MaxiK) channel is necessary for its cell surface expression.MAL mediates apical transport of secretory proteins in polarized epithelial Madin-Darby canine kidney cells.The unique N-terminal sequence of the BKCa channel α-subunit determines its modulation by β-subunits.Alternatively spliced C-terminal domains regulate the surface expression of large conductance calcium-activated potassium channels.Resistance of leukemia cells to cytarabine chemotherapy is mediated by bone marrow stroma, involves cell-surface equilibrative nucleoside transporter-1 removal and correlates with patient outcome.Smooth muscle cholesterol enables BK β1 subunit-mediated channel inhibition and subsequent vasoconstriction evoked by alcohol.
P2860
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P2860
Apical sorting of a voltage- and Ca2+-activated K+ channel alpha -subunit in Madin-Darby canine kidney cells is independent of N-glycosylation
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
@zh-hans
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@zh-my
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@zh-sg
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name
Apical sorting of a voltage- a ...... independent of N-glycosylation
@en
Apical sorting of a voltage- a ...... ndependent of N-glycosylation.
@nl
type
label
Apical sorting of a voltage- a ...... independent of N-glycosylation
@en
Apical sorting of a voltage- a ...... ndependent of N-glycosylation.
@nl
prefLabel
Apical sorting of a voltage- a ...... independent of N-glycosylation
@en
Apical sorting of a voltage- a ...... ndependent of N-glycosylation.
@nl
P2093
P2860
P356
P1476
Apical sorting of a voltage- a ...... independent of N-glycosylation
@en
P2093
A González
A Norambuena
M Bravo-Zehnder
P2860
P304
13114-13119
P356
10.1073/PNAS.240455697
P407
P577
2000-11-01T00:00:00Z