Increased pfmdr1 gene copy number and the decline in pfcrt and pfmdr1 resistance alleles in Ghanaian Plasmodium falciparum isolates after the change of anti-malarial drug treatment policy.
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Genetic diversity of Plasmodium falciparum isolates from uncomplicated malaria cases in Ghana over a decadeAssessment of copy number variation in genes related to drug resistance in Plasmodium vivax and Plasmodium falciparum isolates from the Brazilian Amazon and a systematic review of the literatureMolecular markers of anti-malarial drug resistance in Central, West and East African children with severe malaria.Molecular surveillance of Plasmodium falciparum resistance to artemisinin-based combination therapies in the Democratic Republic of Congo.Use of proscribed chloroquine is associated with an increased risk of pfcrt T76 mutation in some parts of Ghana.Surveillance of artemether-lumefantrine associated Plasmodium falciparum multidrug resistance protein-1 gene polymorphisms in TanzaniaPolymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine.Temporal and seasonal changes of genetic polymorphisms associated with altered drug susceptibility to chloroquine, lumefantrine, and quinine in Guinea-Bissau between 2003 and 2012Prevalence of Plasmodium falciparum anti-malarial resistance-associated polymorphisms in pfcrt, pfmdr1 and pfnhe1 in Muheza, Tanzania, prior to introduction of artemisinin combination therapy.Impact of antimalarial treatment and chemoprevention on the drug sensitivity of malaria parasites isolated from ugandan children.Policy analysis for deciding on a malaria vaccine RTS,S in Tanzania.Prevalence of crt and mdr-1 mutations in Plasmodium falciparum isolates from Grande Comore island after withdrawal of chloroquineA SYBR Green 1-based in vitro test of susceptibility of Ghanaian Plasmodium falciparum clinical isolates to a panel of anti-malarial drugs.Plasmodium falciparum Genetic Diversity in Continental Equatorial Guinea before and after Introduction of Artemisinin-Based Combination TherapyReduced ex vivo susceptibility of Plasmodium falciparum after oral artemether-lumefantrine treatment in Mali.The emerging threat of artemisinin resistance in malaria: focus on artemether-lumefantrine.Efficacy of Artesunate/Amodiaquine in the Treatment of Uncomplicated Malaria among Children in Ghana.pfmdr1 (Plasmodium falciparum multidrug drug resistance gene 1): a pivotal factor in malaria resistance to artemisinin combination therapies.Analysis of major genome loci underlying artemisinin resistance and pfmdr1 copy number in pre- and post-ACTs in western Kenya.Prevalence of pfmdr1 alleles associated with artemether-lumefantrine tolerance/resistance in Maputo before and after the implementation of artemisinin-based combination therapy.Genetic resistance to purine nucleoside phosphorylase inhibition in Plasmodium falciparum.Prevalence of Plasmodium falciparum delayed clearance associated polymorphisms in adaptor protein complex 2 mu subunit (pfap2mu) and ubiquitin specific protease 1 (pfubp1) genes in Ghanaian isolates.
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Increased pfmdr1 gene copy number and the decline in pfcrt and pfmdr1 resistance alleles in Ghanaian Plasmodium falciparum isolates after the change of anti-malarial drug treatment policy.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 30 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Increased pfmdr1 gene copy num ...... alarial drug treatment policy.
@en
Increased pfmdr1 gene copy num ...... alarial drug treatment policy.
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type
label
Increased pfmdr1 gene copy num ...... alarial drug treatment policy.
@en
Increased pfmdr1 gene copy num ...... alarial drug treatment policy.
@nl
prefLabel
Increased pfmdr1 gene copy num ...... alarial drug treatment policy.
@en
Increased pfmdr1 gene copy num ...... alarial drug treatment policy.
@nl
P2093
P2860
P50
P921
P356
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Increased pfmdr1 gene copy num ...... alarial drug treatment policy.
@en
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Benjamin Abuaku
Charles A Narh
Christiana O Onwona
Christopher Duplessis
Daniel D Binnah
Kwadwo A Koram
Mary M Tamakloe
Neils B Quashie
Sena A Matrevi
Vera S Opoku
P2860
P2888
P356
10.1186/1475-2875-12-377
P577
2013-10-30T00:00:00Z
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P6179
1052147288