An ezrin/calpain/PI3K/AMPK/eNOSs1179 signaling cascade mediating VEGF-dependent endothelial nitric oxide production.
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Netrin-1 prevents ischemia/reperfusion-induced myocardial infarction via a DCC/ERK1/2/eNOS s1177/NO/DCC feed-forward mechanismCalpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of diseaseCalpain activity is essential in skin wound healing and contributes to scar formation.Inhibition of calpain reduces oxidative stress and attenuates endothelial dysfunction in diabetes.Mechanism and role of high density lipoprotein-induced activation of AMP-activated protein kinase in endothelial cells.Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase.Multiple neurotrophic effects of VEGF on cultured neurons.Netrin-1 improves post-injury cardiac function in vivo via DCC/NO-dependent preservation of mitochondrial integrity, while attenuating autophagy.Proteases in cardiometabolic diseases: Pathophysiology, molecular mechanisms and clinical applicationsThe calpain/calpastatin system has opposing roles in growth and metastatic dissemination of melanoma.Netrin-1 abrogates ischemia/reperfusion-induced cardiac mitochondrial dysfunction via nitric oxide-dependent attenuation of NOX4 activation and recoupling of NOS.AMPK-regulated and Akt-dependent enhancement of glucose uptake is essential in ischemic preconditioning-alleviated reperfusion injuryPalmitic acid acutely stimulates glucose uptake via activation of Akt and ERK1/2 in skeletal muscle cells.Hyperhomocysteinemia and hyperglycemia induce and potentiate endothelial dysfunction via μ-calpain activation.Expression of ezrin, CD44, and VEGF in giant cell tumor of bone and its significance.N-terminal domain of soluble epoxide hydrolase negatively regulates the VEGF-mediated activation of endothelial nitric oxide synthase.μ-Calpain as a Novel Target for Impairment of Nitric Oxide-Mediated Vascular Relaxation in Diabetes: A Mini Review.Calpain inhibition decreases myocardial apoptosis in a swine model of chronic myocardial ischemia.Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation.Role of reactive oxygen and nitrogen species in the vascular responses to inflammation.VEGF Receptor-2-Linked PI3K/Calpain/SIRT1 Activation Mediates Retinal Arteriolar Dilations to VEGF and Shear Stress.Ezrin regulates focal adhesion and invadopodia dynamics by altering calpain activity to promote breast cancer cell invasion.ICAM-1-activated Src and eNOS signaling increase endothelial cell surface PECAM-1 adhesivity and neutrophil transmigration.Particulate matter air pollution disrupts endothelial cell barrier via calpain-mediated tight junction protein degradation.Obestatin induced recovery of myocardial dysfunction in type 1 diabetic rats: underlying mechanismsAcute erythropoietin cardioprotection is mediated by endothelial response.Calpains and Coronary Vascular DiseaseMechanisms and consequences of endothelial nitric oxide synthase dysfunction in hypertensionIntralipid, a clinically safe compound, protects the heart against ischemia-reperfusion injury more efficiently than cyclosporine-A.Cardiac vulnerability to ischemia/reperfusion injury drastically increases in late pregnancy.Heart failure caused by molecularly targeted therapies for cancer.Antiangiogenic-induced hypertension: the molecular basis of signaling network.Anti-VEGF-Induced Hypertension: a Review of Pathophysiology and Treatment Options.Protein Phosphotyrosine Phosphatase 1B (PTP1B) in Calpain-dependent Feedback Regulation of Vascular Endothelial Growth Factor Receptor (VEGFR2) in Endothelial Cells: IMPLICATIONS IN VEGF-DEPENDENT ANGIOGENESIS AND DIABETIC WOUND HEALING.25-Hydroxycholesterol impairs endothelial function and vasodilation by uncoupling and inhibiting endothelial nitric oxide synthase.Ezrin Orchestrates Signal Transduction in Airway Cells.Activation of calpains mediates early lung neutrophilic inflammation in ventilator-induced lung injury.Activation of SIRT1 Attenuates Klotho Deficiency-Induced Arterial Stiffness and Hypertension by Enhancing AMP-Activated Protein Kinase Activity.Rosiglitazone inhibits high glucose-induced apoptosis in human umbilical vein endothelial cells through the PI3K/Akt/eNOS pathway.Defective Protein Catabolism in Atherosclerotic Vascular Inflammation.
P2860
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P2860
An ezrin/calpain/PI3K/AMPK/eNOSs1179 signaling cascade mediating VEGF-dependent endothelial nitric oxide production.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
An ezrin/calpain/PI3K/AMPK/eNO ...... elial nitric oxide production.
@en
An ezrin/calpain/PI3K/AMPK/eNO ...... elial nitric oxide production.
@nl
type
label
An ezrin/calpain/PI3K/AMPK/eNO ...... elial nitric oxide production.
@en
An ezrin/calpain/PI3K/AMPK/eNO ...... elial nitric oxide production.
@nl
prefLabel
An ezrin/calpain/PI3K/AMPK/eNO ...... elial nitric oxide production.
@en
An ezrin/calpain/PI3K/AMPK/eNO ...... elial nitric oxide production.
@nl
P2093
P2860
P1433
P1476
An ezrin/calpain/PI3K/AMPK/eNO ...... elial nitric oxide production.
@en
P2093
P2860
P356
10.1161/CIRCRESAHA.108.178467
P577
2008-11-26T00:00:00Z