Structure-based rational design of a phosphotriesterase.
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A 5000-Fold Increase in the Specificity of a Bacterial Phosphotriesterase for Malathion through Combinatorial Active Site Mutagenesis300-Fold Increase in Production of the Zn2+-Dependent Dechlorinase TrzN in Soluble Form via Apoenzyme StabilizationMining electron density for functionally relevant protein polysterism in crystal structures.Kinetics and efficacy of an organophosphorus hydrolase in a rodent model of methyl-parathion poisoning.Pharmacokinetics of OpdA, an organophosphorus hydrolase, in the African green monkeyUse of OpdA, an organophosphorus (OP) hydrolase, prevents lethality in an African green monkey model of acute OP poisoningFrom protein engineering to immobilization: promising strategies for the upgrade of industrial enzymesCurrent and emerging strategies for organophosphate decontamination: special focus on hyperstable enzymes.The evolution of new enzyme function: lessons from xenobiotic metabolizing bacteria versus insecticide-resistant insects.An isofenphos-methyl hydrolase (Imh) capable of hydrolyzing the P-O-Z moiety of organophosphorus pesticides containing an aryl or heterocyclic group.Impact of phenylalanines outside the dimer interface on phosphotriesterase stability and function.Combinatorial evolution of phosphotriesterase toward a robust malathion degrader by hierarchical iteration mutagenesis.Mutation of outer-shell residues modulates metal ion co-ordination strength in a metalloenzyme
P2860
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P2860
Structure-based rational design of a phosphotriesterase.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 05 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Structure-based rational design of a phosphotriesterase.
@en
Structure-based rational design of a phosphotriesterase.
@nl
type
label
Structure-based rational design of a phosphotriesterase.
@en
Structure-based rational design of a phosphotriesterase.
@nl
prefLabel
Structure-based rational design of a phosphotriesterase.
@en
Structure-based rational design of a phosphotriesterase.
@nl
P2093
P2860
P50
P356
P1476
Structure-based rational design of a phosphotriesterase.
@en
P2093
Anthony Herlt
Christopher Easton
Irene Horne
Jeevan Khurana
Kahli Weir
Robyn J Russell
Tara D Sutherland
P2860
P304
P356
10.1128/AEM.00629-09
P407
P577
2009-06-05T00:00:00Z