Inhibiting Plasmodium falciparum growth and heme detoxification pathway using heme-binding DNA aptamers
about
Challenges and opportunities for small molecule aptamer developmentA novel way to grow hemozoin-like crystals in vitro and its use to screen for hemozoin inhibiting antimalarial compoundsDendrimeric template of Plasmodium falciparum histidine rich protein II repeat motifs bearing Asp→Asn mutation exhibits heme binding and β-hematin formation.Selection of binding targets in parasites using phage-display and aptamer libraries in vivo and in vitro.Molecular and Functional Characterization of ssDNA Aptamers that Specifically Bind Leishmania infantum PABPFrom the genome to the phenome: tools to understand the basic biology of Plasmodium falciparum.Antiplasmodial drug targets: a patent review (2000 - 2013).Effect of pH and oxygen on biofilm formation in acute otitis media associated NTHi clinical isolates.In vivo uptake of a haem analogue Zn protoporphyrin IX by the human malaria parasite P. falciparum-infected red blood cells.Aptamer Technology: Adjunct Therapy for Malaria.
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Inhibiting Plasmodium falciparum growth and heme detoxification pathway using heme-binding DNA aptamers
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Inhibiting Plasmodium falcipar ...... sing heme-binding DNA aptamers
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Inhibiting Plasmodium falcipar ...... ing heme-binding DNA aptamers.
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type
label
Inhibiting Plasmodium falcipar ...... sing heme-binding DNA aptamers
@en
Inhibiting Plasmodium falcipar ...... ing heme-binding DNA aptamers.
@nl
prefLabel
Inhibiting Plasmodium falcipar ...... sing heme-binding DNA aptamers
@en
Inhibiting Plasmodium falcipar ...... ing heme-binding DNA aptamers.
@nl
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Inhibiting Plasmodium falcipar ...... sing heme-binding DNA aptamers
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Jacquin C Niles
Joseph L Derisi
Michael A Marletta
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P304
13266-13271
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10.1073/PNAS.0906370106
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P577
2009-07-24T00:00:00Z