Cancer stem-like cell properties are regulated by EGFR/AKT/β-catenin signaling and preferentially inhibited by gefitinib in nasopharyngeal carcinoma.
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Novel cancer chemotherapy hits by molecular topology: dual Akt and Beta-catenin inhibitorsAfatinib radiosensitizes head and neck squamous cell carcinoma cells by targeting cancer stem cells.Modeling nasopharyngeal carcinoma in three dimensionsTargeting Head and Neck Cancer Stem Cells: Current Advances and Future Challengesβ1, 4-N-acetylgalactosaminyltransferase III modulates cancer stemness through EGFR signaling pathway in colon cancer cells.E3-ligase Skp2 predicts poor prognosis and maintains cancer stem cell pool in nasopharyngeal carcinoma.Evaluation of cancer stem cell markers CD133, CD44, CD24: association with AKT isoforms and radiation resistance in colon cancer cells.PTPRG suppresses tumor growth and invasion via inhibition of Akt signaling in nasopharyngeal carcinoma.Cytokine-induced killer cells efficiently kill stem-like cancer cells of nasopharyngeal carcinoma via the NKG2D-ligands recognitionNuclear β-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancer.Targeting cancer stem cells: emerging role of Nanog transcription factorGlutaredoxin 3 promotes nasopharyngeal carcinoma growth and metastasis via EGFR/Akt pathway and independent of ROS.Metalloprotease-disintegrin ADAM12 actively promotes the stem cell-like phenotype in claudin-low breast cancerEGFR induces DNA decomposition via phosphodiester bond cleavageEGFR signaling and autophagy dependence for growth, survival, and therapy resistance.Cancer biomarker discovery: current status and future perspectives.Tumor heterogeneity and cancer stem cell paradigm: updates in concept, controversies and clinical relevance.Cancer stem-like cell: a novel target for nasopharyngeal carcinoma therapy.Overexpression of chromosome 14 open reading frame 166 correlates with disease progression and poorer prognosis in human NPC.Signal transduction in cancerPrognostic significance of the EGFR pathway in nasopharyngeal carcinoma: a systematic review and meta-analysis.Silencing of fused toes homolog enhances cisplatin sensitivity in cervical cancer cells by inhibiting epidermal growth factor receptor-mediated repair of DNA damage.β-Catenin is important for cancer stem cell generation and tumorigenic activity in nasopharyngeal carcinoma.Galectin-3 modulates the EGFR signalling-mediated regulation of Sox2 expression via c-Myc in lung cancer.Wnt-C59 arrests stemness and suppresses growth of nasopharyngeal carcinoma in mice by inhibiting the Wnt pathway in the tumor microenvironment.MTA1 overexpression induces cisplatin resistance in nasopharyngeal carcinoma by promoting cancer stem cells properties.A novel bidirectional positive-feedback loop between Wnt-β-catenin and EGFR-ERK plays a role in context-specific modulation of epithelial tissue regeneration.EGFR Family Members' Regulation of Autophagy Is at a Crossroads of Cell Survival and Death in Cancer.Adamantinomatous craniopharyngiomas express tumor stem cell markers in cells with activated Wnt signaling: further evidence for the existence of a tumor stem cell niche?Honokiol suppresses renal cancer cells' metastasis via dual-blocking epithelial-mesenchymal transition and cancer stem cell properties through modulating miR-141/ZEB2 signaling.Mechanistic Evaluation and Translational Signature of Gemcitabine-induced Chemoresistance by Quantitative Phosphoproteomics Analysis with iTRAQ Labeling Mass Spectrometry.Cisplatin triggers cancer stem cell enrichment in platinum-resistant cells through NF-κB-TNFα-PIK3CA loop.Models of human adamantinomatous craniopharyngioma tissue: Steps toward an effective adjuvant treatment.EGFRwt/vIII-PKM2-β-catenin cascade affects proliferation and chemo-sensitivity in head and neck squamous cell carcinoma.Factors Secreted by Cancer-Associated Fibroblasts that Sustain Cancer Stem Properties in Head and Neck Squamous Carcinoma Cells as Potential Therapeutic Targets
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Cancer stem-like cell properties are regulated by EGFR/AKT/β-catenin signaling and preferentially inhibited by gefitinib in nasopharyngeal carcinoma.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 08 April 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Cancer stem-like cell properti ...... b in nasopharyngeal carcinoma.
@en
Cancer stem-like cell properti ...... b in nasopharyngeal carcinoma.
@nl
type
label
Cancer stem-like cell properti ...... b in nasopharyngeal carcinoma.
@en
Cancer stem-like cell properti ...... b in nasopharyngeal carcinoma.
@nl
prefLabel
Cancer stem-like cell properti ...... b in nasopharyngeal carcinoma.
@en
Cancer stem-like cell properti ...... b in nasopharyngeal carcinoma.
@nl
P2093
P2860
P356
P1433
P1476
Cancer stem-like cell properti ...... b in nasopharyngeal carcinoma.
@en
P2093
Du-Xin Sun
Gong Zhang
Guang-Hui Xiao
Joseph R Testa
Kai-Tai Yao
Qiu-Zhen Liu
Xi-Qing Li
Xiao-Bo Miao
Xu-Bin Deng
P2860
P304
P356
10.1111/FEBS.12226
P407
P577
2013-04-08T00:00:00Z