Transforming growth factor beta: tumor suppressor or promoter? Are host immune cells the answer? - Test2 - elhamkhani - TriplyDB

Transforming growth factor beta: tumor suppressor or promoter? Are host immune cells the answer?

Transforming growth factor beta: tumor suppressor or promoter? Are host immune cells the answer?

http://www.wikidata.org/entity/Q37326107

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Cathepsin H regulated by the thyroid hormone receptors associate with tumor invasion in human hepatoma cells The role of the myofibroblast in tumor stroma remodeling The role of integrins in TGFβ activation in the tumour stroma Initial steps of metastasis: cell invasion and endothelial transmigration Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis TGF-β sensitivity is determined by N-linked glycosylation of the type II TGF-β receptor Inhibitory effect of a TGFbeta receptor type-I inhibitor, Ki26894, on invasiveness of scirrhous gastric cancer cells.Decreased levels of active SMAD2 correlate with poor prognosis in gastric cancer.TGF-β signaling in myeloid cells is required for tumor metastasis.Transforming growth factor-(beta)s and mammary gland involution; functional roles and implications for cancer progression.Regulation of tumor immune surveillance and tumor immune subversion by tgf-Beta Phosphorylated smad2 in advanced stage gastric carcinoma.TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progression Transforming growth factor-β1 signaling represses testicular steroidogenesis through cross-talk with orphan nuclear receptor Nur77.TGFβ in T cell biology and tumor immunity: Angel or devil?Cytosolic phospholipase A2alpha and peroxisome proliferator-activated receptor gamma signaling pathway counteracts transforming growth factor beta-mediated inhibition of primary and transformed hepatocyte growth Breast cancer at bone metastatic sites: recent discoveries and treatment targets.The mammary gland microenvironment directs progenitor cell fate in vivo Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition.Leucine-rich α-2-glycoprotein promotes TGFβ1-mediated growth suppression in the Lewis lung carcinoma cell lines Transforming growth factor-β and smooth muscle differentiation Acquired genetic and functional alterations associated with transforming growth factor beta type I resistance in Hep3B human hepatocellular carcinoma cell line.Maspin reprograms the gene expression profile of prostate carcinoma cells for differentiation.Reprogramming during epithelial to mesenchymal transition under the control of TGFβ Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties.Gr-1+CD11b+ cells are responsible for tumor promoting effect of TGF-β in breast cancer progression CD33⁺/p-STAT1⁺ double-positive cell as a prognostic factor for stage IIIa gastric cancer.Inhibition of Soluble Tumor Necrosis Factor Prevents Chemically Induced Carcinogenesis in Mice The metastatic niche: adapting the foreign soil.Integrin-mediated transforming growth factor-beta activation, a potential therapeutic target in fibrogenic disorders.Effective chemoimmunotherapy with anti-TGFβ antibody and cyclophosphamide in a mouse model of breast cancer.Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor.Emerging therapeutic targets in breast cancer bone metastasis.Nanoparticle-delivered transforming growth factor-β siRNA enhances vaccination against advanced melanoma by modifying tumor microenvironment.The crosstalk of RAS with the TGF-β family during carcinoma progression and its implications for targeted cancer therapy.Microbial deprivation, inflammation and cancer.Tumor microenvironment: a main actor in the metastasis process.Growth/differentiation factor-15: prostate cancer suppressor or promoter?The reactive stroma microenvironment and prostate cancer progression.Thyroid hormone actions in liver cancer.

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P2860

Transforming growth factor beta: tumor suppressor or promoter? Are host immune cells the answer?

http://www.wikidata.org/entity/Q37326107

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2008 nî lūn-bûn

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Transforming growth factor bet ...... host immune cells the answer?

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Transforming growth factor bet ...... host immune cells the answer?

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Transforming growth factor bet ...... host immune cells the answer?

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0008-5472.CAN-08-2556

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Cancer Research

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Li Yang

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Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

TGF-beta: a mobile purveyor of immune privilege

TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4

Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis

Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin

Molecular predictors of survival after adjuvant chemotherapy for colon cancer

Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

Stromal fibroblasts in cancer initiation and progression

Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia.

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9107-9111

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10.1158/0008-5472.CAN-08-2556

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Harold L. Moses

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