Lessons from polyoma middle T antigen on signaling and transformation: A DNA tumor virus contribution to the war on cancer.
about
Retroviral oncogenes: a historical primerModeling human endothelial cell transformation in vascular neoplasiasPolyoma small T antigen triggers cell death via mitotic catastropheThe p110α and p110β isoforms of PI3K play divergent roles in mammary gland development and tumorigenesis.In Vitro and In Vivo Models for the Study of Human Polyomavirus InfectionA Transformation-Defective Polyomavirus Middle T Antigen with a Novel Defect in PI3 Kinase Signaling.Global Analysis of Mouse Polyomavirus Infection Reveals Dynamic Regulation of Viral and Host Gene Expression and Promiscuous Viral RNA EditingHerpes simplex virus requires VP11/12 to induce phosphorylation of the activation loop tyrosine (Y394) of the Src family kinase Lck in T lymphocytes.Polyoma virus-induced osteosarcomas in inbred strains of mice: host determinants of metastasis.Herpes simplex virus protein kinases US3 and UL13 modulate VP11/12 phosphorylation, virion packaging, and phosphatidylinositol 3-kinase/Akt signaling activityMerkel cell polyomavirus-infected Merkel cell carcinoma cells require expression of viral T antigens.Phosphatidylinositol 3-kinase: the oncoprotein.The phosphatidylinositol 3-kinase (PI3K) isoform dependence of tumor formation is determined by the genetic mode of PI3K pathway activation rather than by tissue type.Shp2 suppresses PyMT-induced transformation in mouse fibroblasts by inhibiting Stat3 activity.Transgenic expression of polyomavirus middle T antigen in the mouse prostate gives rise to carcinoma.Cellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens.Lessons in signaling and tumorigenesis from polyomavirus middle T antigen.ErbB3 ablation impairs PI3K/Akt-dependent mammary tumorigenesis.Mammary transplantation of stromal cells and carcinoma cells in C57BL/6J miceMonitoring therapeutic efficacy of sunitinib using [(18)F]FDG and [(18)F]FMISO PET in an immunocompetent model of luminal B (HER2-positive)-type mammary carcinomaMammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis.Viral proteins and Src family kinases: Mechanisms of pathogenicity from a "liaison dangereuse".The polyomavirus middle T-antigen oncogene activates the Hippo pathway tumor suppressor Lats in a Src-dependent manner.Polyomavirus middle T-antigen is a transmembrane protein that binds signaling proteins in discrete subcellular membrane sites.Transformation by Polyomavirus Middle T Antigen Involves a Unique Bimodal Interaction with the Hippo Effector YAP.Stat3 and gap junctions in normal and lung cancer cells.Role of herpes simplex virus VP11/12 tyrosine-based motifs in binding and activation of the Src family kinase Lck and recruitment of p85, Grb2, and Shc.The Human Polyomavirus Middle and Alternative T-Antigens; Thoughts on Roles and Relevance to Cancer.
P2860
Q24611142-4D2D2FD2-DCDD-4B50-946C-B0F2A0D5D6BBQ26860203-DDDC4DA3-7392-4AE4-8066-C37435E45E0FQ27310118-E4C3BEAB-965C-4D97-9C9F-7776185601BEQ27851848-7EFDADFD-B871-453D-A4EE-926637C336AFQ28074684-0791FE5E-2570-4626-8A95-1D17C220D17DQ30008815-D96F1AF4-0D38-4EA8-9AD3-88FEE1315E38Q30009096-C800B18E-927B-49E8-8300-9B85D19C5E94Q30157107-596F3797-7E66-40F2-BCD0-E69D45922C22Q33527003-2EB691C1-8BAA-4730-B738-282686CA81BAQ33743987-AE58F777-B2AB-4C2D-81A0-7050304249F1Q33966574-4F55FD51-4128-4E90-94CE-C0DD2E17E6C8Q34203861-E61F6963-9F0B-4A73-BC86-440CFB24DE0FQ34262144-29C89E85-3C79-4EA5-884D-8C41630224E4Q34433715-AA4E85C7-151B-4BA4-88F4-A51961D8A54EQ34982720-CF56F8EA-DF78-444E-AC3D-10BE6618A185Q34985587-345A7A27-7F85-48E7-8C15-B13D27F99709Q35000523-90F8A291-B47F-4ECB-B782-97E2904401AEQ35479646-13035269-0368-44F9-A713-6013A6FE69A7Q35536378-AC73E0C1-1F54-4400-8D88-7EE9B08FB8A8Q35703904-F8F10E1D-F795-4717-B856-64C223146DA5Q35779175-6E3FD729-1D06-4B9B-AE02-B6002DA4CEA1Q38156886-44C7645D-3104-4C44-A356-5B5C6A8011C6Q38943407-33203DD5-F6A6-400E-9BD6-F2AEDE6244E3Q39608658-7C78BB82-CA37-4E50-888E-143C0D1CE56FQ40668562-A45C159E-A84E-4386-BF65-FB6E9529FD7BQ41457047-0B2A25DD-11A0-44FD-9B53-74EC74C6BE7DQ41894103-3431475D-399C-42BE-84FB-D157A963A3E3Q52641622-CA45CE14-B592-4F5B-BA6B-9CE4CB0E2FFF
P2860
Lessons from polyoma middle T antigen on signaling and transformation: A DNA tumor virus contribution to the war on cancer.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Lessons from polyoma middle T ...... ribution to the war on cancer.
@en
Lessons from polyoma middle T ...... ribution to the war on cancer.
@nl
type
label
Lessons from polyoma middle T ...... ribution to the war on cancer.
@en
Lessons from polyoma middle T ...... ribution to the war on cancer.
@nl
prefLabel
Lessons from polyoma middle T ...... ribution to the war on cancer.
@en
Lessons from polyoma middle T ...... ribution to the war on cancer.
@nl
P2860
P1433
P1476
Lessons from polyoma middle T ...... ribution to the war on cancer.
@en
P2093
Brian S Schaffhausen
Thomas M Roberts
P2860
P304
P356
10.1016/J.VIROL.2008.09.042
P407
P577
2008-11-20T00:00:00Z