The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth
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WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activityWnts talking with the TGF-β superfamily: WISPers about modulation of osteoarthritisRegulation of pancreatic function by connective tissue growth factor (CTGF, CCN2)Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targetsPentoxifylline Inhibits WNT Signalling in β-Cateninhigh Patient-Derived Melanoma Cell PopulationsRemodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer.Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant gliomaInvestigating microenvironmental regulation of human chordoma cell behaviourHypoxia, inflammation, and the tumor microenvironment in metastatic diseaseThe CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis.Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinomamiR-205 expression promotes cell proliferation and migration of human cervical cancer cellsStructural ECM components in the premetastatic and metastatic niche.MicroRNA-145 is downregulated in glial tumors and regulates glioma cell migration by targeting connective tissue growth factorCooperative interaction of CTGF and TGF-β in animal models of fibrotic disease.The G protein-coupled receptor 30 is up-regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) in breast cancer cells and cardiomyocytesReduced CTGF expression promotes cell growth, migration, and invasion in nasopharyngeal carcinomaWISP1/CCN4: a potential target for inhibiting prostate cancer growth and spread to bone.Downregulation of connective tissue growth factor inhibits the growth and invasion of gastric cancer cells and attenuates peritoneal disseminationInhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma.Potential prognostic biomarkers for bone metastasis from hepatocellular carcinoma.TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growthAntitumor Activity of a Novel Sphingosine-1-Phosphate 2 Antagonist, AB1, in Neuroblastoma.Convergent signaling in the regulation of connective tissue growth factor in malignant mesothelioma: TGFβ signaling and defects in the Hippo signaling cascade.Connective tissue growth factor is overexpressed in human hepatocellular carcinoma and promotes cell invasion and growth.Matricellular proteins in drug delivery: Therapeutic targets, active agents, and therapeutic localizationHypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity.Loss of connective tissue growth factor as an unfavorable prognosis factor activates miR-18b by PI3K/AKT/C-Jun and C-Myc and promotes cell growth in nasopharyngeal carcinomaCTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancerDifferential expression of CCN family members CYR611, CTGF and NOV in gastric cancer and their association with disease progressionP38 pathway as a key downstream signal of connective tissue growth factor to regulate metastatic potential in non-small-cell lung cancer.Novel agents for the treatment of adenocarcinoma of the pancreas.Targeting connective tissue growth factor (CTGF) in acute lymphoblastic leukemia preclinical models: anti-CTGF monoclonal antibody attenuates leukemia growth.CTGF is a therapeutic target for metastatic melanoma.Novel therapeutic strategies targeting tumor-stromal interactions in pancreatic cancer.Inflammation and pancreatic cancer: disease promoter and new therapeutic target.Selected terpenoids from medicinal plants modulate endoplasmic reticulum stress in metabolic disorders.Deregulated expression of connective tissue growth factor (CTGF/CCN2) is linked to poor outcome in human cancer.The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis.What are the macrophages and stellate cells doing in pancreatic adenocarcinoma?
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The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The role of tumor cell-derived ...... N2) in pancreatic tumor growth
@en
The role of tumor cell-derived connective tissue growth factor
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type
label
The role of tumor cell-derived ...... N2) in pancreatic tumor growth
@en
The role of tumor cell-derived connective tissue growth factor
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prefLabel
The role of tumor cell-derived ...... N2) in pancreatic tumor growth
@en
The role of tumor cell-derived connective tissue growth factor
@nl
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P2860
P1433
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The role of tumor cell-derived ...... N2) in pancreatic tumor growth
@en
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Amato J Giaccia
Christine M Ham
Edward E Graves
George P Yang
Jonathan Feazell
Kevin L Bennewith
Neeraja Kambham
P2860
P304
P356
10.1158/0008-5472.CAN-08-0987
P407
P577
2009-02-01T00:00:00Z