A broad screen for targets of immune complexes decorating arthritic joints highlights deposition of nucleosomes in rheumatoid arthritis.
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Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints.Immune complexes regulate bone metabolism through FcRγ signallingRabphilin-3A as a Targeted Autoantigen in Lymphocytic Infundibulo-neurohypophysitis.c-Fms-mediated differentiation and priming of monocyte lineage cells play a central role in autoimmune arthritis.Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritisRelatives without rheumatoid arthritis show reactivity to anti-citrullinated protein/peptide antibodies that are associated with arthritis-related traits: studies of the etiology of rheumatoid arthritis.Proteoglycan-induced arthritis and recombinant human proteoglycan aggrecan G1 domain-induced arthritis in BALB/c mice resembling two subtypes of rheumatoid arthritis.Induced expression of FcγRIIIa (CD16a) on CD4+ T cells triggers generation of IFN-γhigh subset.Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 'shared epitope' allelesCrystals, inflammation, and osteoarthritis.Release and activity of histone in diseases.Extracellular histones inhibit efferocytosis.Promotion of Inflammatory Arthritis by Interferon Regulatory Factor 5 in a Mouse Model.A Selective Inhibitor of Human C-reactive Protein Translation Is Efficacious In Vitro and in C-reactive Protein Transgenic Mice and HumansSoluble biglycan: a potential mediator of cartilage degradation in osteoarthritisAssociation of fine specificity and repertoire expansion of anticitrullinated peptide antibodies with rheumatoid arthritis associated interstitial lung disease.Anti-citrullinated peptide autoantibodies, human leukocyte antigen shared epitope and risk of future rheumatoid arthritis: a nested case-control study.Protein array diagnostics for guiding therapy in rheumatoid arthritis.Development and deployment of antigen arrays for investigation of B-cell fine specificity in autoimmune disease.B effector cells in rheumatoid arthritis and experimental arthritis.The role of extracellular histone in organ injury.Arthritis models: usefulness and interpretation.Novel multiplex technology for diagnostic characterization of rheumatoid arthritis.Identification of an immunodominant peptide from citrullinated tenascin-C as a major target for autoantibodies in rheumatoid arthritis.The synovium in rheumatoid arthritisModulation of matrix metalloproteinase production by rheumatoid arthritis synovial fibroblasts after cadherin 11 engagement.Extracellular histones disarrange vasoactive mediators release through a COX-NOS interaction in human endothelial cells.Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor.The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes.Antibody Responses to Citrullinated and Non-Citrullinated Antigens in the Sputum of Subjects with and At-Risk for Rheumatoid Arthritis.Rheumatoid arthritis synovial tissue harbours dominant B-cell and plasma-cell clones associated with autoreactivity.
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A broad screen for targets of immune complexes decorating arthritic joints highlights deposition of nucleosomes in rheumatoid arthritis.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 31 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A broad screen for targets of ...... somes in rheumatoid arthritis.
@en
A broad screen for targets of ...... somes in rheumatoid arthritis.
@nl
type
label
A broad screen for targets of ...... somes in rheumatoid arthritis.
@en
A broad screen for targets of ...... somes in rheumatoid arthritis.
@nl
prefLabel
A broad screen for targets of ...... somes in rheumatoid arthritis.
@en
A broad screen for targets of ...... somes in rheumatoid arthritis.
@nl
P2093
P2860
P356
P1476
A broad screen for targets of ...... somes in rheumatoid arthritis.
@en
P2093
Barry P Simmons
Beren H Tomooka
Christophe Benoist
Diane Mathis
Hidde Ploegh
John Wright
Marc Monestier
Maya BenBarak
Thomas S Thornhill
William H Robinson
P2860
P304
15867-15872
P356
10.1073/PNAS.0908032106
P407
P577
2009-08-31T00:00:00Z