Forced expression of tropomyosin 2 or 3 in v-Ki-ras-transformed fibroblasts results in distinct phenotypic effects.
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The human non-muscle alpha-actinin protein encoded by the ACTN4 gene suppresses tumorigenicity of human neuroblastoma cellsSilencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-betaMutant alpha-actinin-4 promotes tumorigenicity and regulates cell motility of a human lung carcinomaSpecific features of neuronal size and shape are regulated by tropomyosin isoforms.Sorting of a nonmuscle tropomyosin to a novel cytoskeletal compartment in skeletal muscle results in muscular dystrophyConnective tissue growth factor in regulation of RhoA mediated cytoskeletal tension associated osteogenesis of mouse adipose-derived stromal cellsv-Src suppresses SHPS-1 expression via the Ras-MAP kinase pathway to promote the oncogenic growth of cells.Calponin repeats regulate actin filament stability and formation of podosomes in smooth muscle cells.Protein expression profiling of lens epithelial cells from Prdx6-depleted mice and their vulnerability to UV radiation exposureSorting of tropomyosin isoforms in synchronised NIH 3T3 fibroblasts: evidence for distinct microfilament populations.Post-transcriptional down-regulation of ROCKI/Rho-kinase through an MEK-dependent pathway leads to cytoskeleton disruption in Ras-transformed fibroblasts.Internal and external paralogy in the evolution of tropomyosin genes in metazoansOpposing roles of the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in Ras-mediated downregulation of tropomyosin.Tropomyosin-based regulation of the actin cytoskeleton in time and space.Overexpression of kinase suppressor of Ras upregulates the high-molecular-weight tropomyosin isoforms in ras-transformed NIH 3T3 fibroblastsHypoxia alters the recruitment of tropomyosins into the actin stress fibres of neuroblastoma cells.The actin cytoskeleton as a sensor and mediator of apoptosisThe tension mounts: stress fibers as force-generating mechanotransducersGamma tropomyosin gene products are required for embryonic development.Caldesmon inhibits nonmuscle cell contractility and interferes with the formation of focal adhesions.From the Cover: Neutralization of terminal differentiation in gliomagenesis.Tropomyosin-2 cDNA lacking the 3' untranslated region riboregulator induces growth inhibition of v-Ki-ras-transformed fibroblastsFarnesyltransferase inhibitors induce dramatic morphological changes of KNRK cells that are blocked by microtubule interfering agents.New insights into the regulation of the actin cytoskeleton by tropomyosin.New approaches to targeting the actin cytoskeleton for chemotherapy.Downregulation of tropomyosin-1 in squamous cell carcinoma of esophagus, the role of Ras signaling and methylation.Role of phosphatidylinositol 4,5-bisphosphate in Ras/Rac-induced disruption of the cortactin-actomyosin II complex and malignant transformation.High molecular weight tropomyosins regulate osteoclast cytoskeletal morphology.A critical role of tropomyosins in TGF-beta regulation of the actin cytoskeleton and cell motility in epithelial cells.Suppression of the tumorigenicity of mutant p53-transformed rat embryo fibroblasts through expression of a newly cloned rat nonmuscle myosin heavy chain-B.Ras- and Raf-induced down-modulation of non-muscle tropomyosin are MEK-independent.N terminus is essential for tropomyosin functions: N-terminal modification disrupts stress fiber organization and abolishes anti-oncogenic effects of tropomyosin-1.Transcriptional basis of KRAS oncogene-mediated cellular transformation in ovarian epithelial cells.Divergent regulation of the sarcomere and the cytoskeleton.Human diploid fibroblasts are resistant to MEK/ERK-mediated disruption of the actin cytoskeleton and invasiveness stimulated by Ras.Tropomyosin isoforms have specific effects on the transcriptome of undifferentiated and differentiated B35 neuroblastoma cells.
P2860
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P2860
Forced expression of tropomyosin 2 or 3 in v-Ki-ras-transformed fibroblasts results in distinct phenotypic effects.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on September 1996
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Forced expression of tropomyos ...... n distinct phenotypic effects.
@en
Forced expression of tropomyos ...... n distinct phenotypic effects.
@nl
type
label
Forced expression of tropomyos ...... n distinct phenotypic effects.
@en
Forced expression of tropomyos ...... n distinct phenotypic effects.
@nl
prefLabel
Forced expression of tropomyos ...... n distinct phenotypic effects.
@en
Forced expression of tropomyos ...... n distinct phenotypic effects.
@nl
P2093
P2860
P356
P1476
Forced expression of tropomyos ...... n distinct phenotypic effects.
@en
P2093
P2860
P304
P356
10.1073/PNAS.93.18.9618
P407
P577
1996-09-01T00:00:00Z