3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
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Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen speciesMyeloperoxidase is involved in H2O2-induced apoptosis of HL-60 human leukemia cellsEndoplasmic reticulum resident proteins of normal human dermal fibroblasts are the major targets for oxidative stress induced by hydrogen peroxideTargeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in micePreparation and Characterization of a Polyclonal Antibody against Brominated ProteinThe balance of powers: Redox regulation of fibrogenic pathways in kidney injuryProtein carbamylation and cardiovascular diseaseInflammation, infection, cancer and all that…the role of paraoxonasesTyrosine modifications in aging2-Thioxanthines Are Mechanism-based Inactivators of Myeloperoxidase That Block Oxidative Stress during InflammationModified Lipids and Lipoproteins in Chronic Kidney Disease: A New Class of Uremic ToxinsElevated levels of protein-bound p-hydroxyphenylacetaldehyde, an amino-acid-derived aldehyde generated by myeloperoxidase, are present in human fatty streaks, intermediate lesions and advanced atherosclerotic lesionsIncreased atherosclerosis in myeloperoxidase-deficient miceMacrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromesReactions of hypochlorous acid with tyrosine and peptidyl-tyrosyl residues give dichlorinated and aldehydic products in addition to 3-chlorotyrosineOxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophagesAscorbate and deferoxamine administration after chlorine exposure decrease mortality and lung injury in miceThe principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity: a potential mechanism for thrombosis in eosinophilic inflammatory statesSevere impairment in early host defense against Candida albicans in mice deficient in myeloperoxidaseNitric oxide is a physiological substrate for mammalian peroxidasesAirborne particulate matter PM2.5 from Mexico City affects the generation of reactive oxygen species by blood neutrophils from asthmatics: an in vitro approachThe roles of myeloperoxidase in coronary artery disease and its potential implication in plaque rupture.Microtubule dysfunction by posttranslational nitrotyrosination of alpha-tubulin: a nitric oxide-dependent mechanism of cellular injuryRational drug design applied to myeloperoxidase inhibition.Electrospray low energy CID and MALDI PSD fragmentations of protonated sulfinamide cross-linked peptides.Production of brominating intermediates by myeloperoxidase. A transhalogenation pathway for generating mutagenic nucleobases during inflammation.Lysine residues direct the chlorination of tyrosines in YXXK motifs of apolipoprotein A-I when hypochlorous acid oxidizes high density lipoprotein.Oxidative cross-linking of tryptophan to glycine restrains matrix metalloproteinase activity: specific structural motifs control protein oxidation.Specific sequence motifs direct the oxygenation and chlorination of tryptophan by myeloperoxidase.Oxidative risk for atherothrombotic cardiovascular disease.MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases.Dysfunctional HDL as a diagnostic and therapeutic targetMyeloperoxidase in human intracranial aneurysms: preliminary evidence.Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan.Effects of protein oxidation on the structure and stability of model discoidal high-density lipoproteinsSite-specific nitration of apolipoprotein A-I at tyrosine 166 is both abundant within human atherosclerotic plaque and dysfunctional.Myeloperoxidase levels predict accelerated progression of coronary atherosclerosis in diabetic patients: insights from intravascular ultrasoundElevated plasma free fatty acids increase cardiovascular risk by inducing plasma biomarkers of endothelial activation, myeloperoxidase and PAI-1 in healthy subjectsChemical and immunochemical detection of 8-halogenated deoxyguanosines at early stage inflammation.Myeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoprotein
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P2860
3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1997
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
3-Chlorotyrosine, a specific m ...... human atherosclerotic intima.
@en
3-Chlorotyrosine, a specific m ...... human atherosclerotic intima.
@nl
type
label
3-Chlorotyrosine, a specific m ...... human atherosclerotic intima.
@en
3-Chlorotyrosine, a specific m ...... human atherosclerotic intima.
@nl
prefLabel
3-Chlorotyrosine, a specific m ...... human atherosclerotic intima.
@en
3-Chlorotyrosine, a specific m ...... human atherosclerotic intima.
@nl
P2860
P921
P356
P1476
3-Chlorotyrosine, a specific m ...... human atherosclerotic intima.
@en
P2093
J W Heinecke
P2860
P304
P356
10.1172/JCI119379
P407
P577
1997-05-01T00:00:00Z