Sphingolipids are essential for differentiation but not growth in Leishmania - Test2 - elhamkhani - TriplyDB

Sphingolipids are essential for differentiation but not growth in Leishmania

Sphingolipids are essential for differentiation but not growth in Leishmania

http://www.wikidata.org/entity/Q37368551

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The essential nature of sphingolipids in plants as revealed by the functional identification and characterization of the Arabidopsis LCB1 subunit of serine palmitoyltransferase Sphingolipid degradation in Leishmania (Leishmania) amazonensis Sterol biosynthesis is required for heat resistance but not extracellular survival in leishmania Bioinformatic Analysis of Leishmania donovani Long-Chain Fatty Acid-CoA Ligase as a Novel Drug Target Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major De novo sphingolipid synthesis is essential for viability, but not for transport of glycosylphosphatidylinositol-anchored proteins, in African trypanosomes.SMP-1, a member of a new family of small myristoylated proteins in kinetoplastid parasites, is targeted to the flagellum membrane in Leishmania Developmentally regulated sphingolipid degradation in Leishmania major Degradation of host sphingomyelin is essential for Leishmania virulence.Phospholipid and sphingolipid metabolism in Leishmania.Cell-free synthesis and functional characterization of sphingolipid synthases from parasitic trypanosomatid protozoa.Metabolic variation during development in culture of Leishmania donovani promastigotes.Identification of a compensatory mutant (lpg2-REV) of Leishmania major able to survive as amastigotes within macrophages without LPG2-dependent glycoconjugates and its significance to virulence and immunization strategies Sphingolipids in parasitic protozoa Role of sphingolipids in microbial pathogenesis Leishmania promastigotes lack phosphatidylserine but bind annexin V upon permeabilization or miltefosine treatment.Modulation of Leishmania ABC protein gene expression through life stages and among drug-resistant parasites.Sphingolipid degradation by Leishmania major is required for its resistance to acidic pH in the mammalian host.Redirection of sphingolipid metabolism toward de novo synthesis of ethanolamine in Leishmania.Comparisons of mutants lacking the Golgi UDP-galactose or GDP-mannose transporters establish that phosphoglycans are important for promastigote but not amastigote virulence in Leishmania major Inositolphosphoceramide metabolism in Trypanosoma cruzi as compared with other trypanosomatids.Leishmania parasites possess a platelet-activating factor acetylhydrolase important for virulence.Moving from unsequenced to sequenced genome: reanalysis of the proteome of Leishmania donovani.Sphingolipids and membrane biology as determined from genetic models.Phospholipid and glycolipid composition of acidocalcisomes of Trypanosoma cruzi.Novel role of sphingolipid synthesis genes in regulating giardial encystation.Leishmania adaptor protein-1 subunits are required for normal lysosome traffic, flagellum biogenesis, lipid homeostasis, and adaptation to temperatures encountered in the mammalian host.Developmentally regulated sphingolipid synthesis in African trypanosomes Lipid metabolism in Trypanosoma brucei Leishmania salvage and remodelling of host sphingolipids in amastigote survival and acidocalcisome biogenesis.Flagellar membrane localization via association with lipid rafts.Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexans Leishmania dihydroxyacetonephosphate acyltransferase LmDAT is important for ether lipid biosynthesis but not for the integrity of detergent resistant membranes.Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs.Sphingosine kinase A is a pleiotropic and essential enzyme for Leishmania survival and virulence.Endocytosis and Sphingolipid Scavenging in Leishmania mexicana Amastigotes.Leishmania (Viannia) braziliensis Inositol Phosphorylceramide: Distinctive Sphingoid Base Composition.Everybody needs sphingolipids, right! Mining for new drug targets in protozoan sphingolipid biosynthesis.Multiple-stage linear ion-trap with high resolution mass spectrometry towards complete structural characterization of phosphatidylethanolamines containing cyclopropane fatty acyl chain in Leishmania infantum.Characterization of inositol phosphorylceramides from Leishmania major by tandem mass spectrometry with electrospray ionization.

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P2860

Sphingolipids are essential for differentiation but not growth in Leishmania

http://www.wikidata.org/entity/Q37368551

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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2003年學術文章

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name

Sphingolipids are essential for differentiation but not growth in Leishmania

@en

Sphingolipids are essential for differentiation but not growth in Leishmania.

@nl

type

label

Sphingolipids are essential for differentiation but not growth in Leishmania

@en

Sphingolipids are essential for differentiation but not growth in Leishmania.

@nl

prefLabel

Sphingolipids are essential for differentiation but not growth in Leishmania

@en

Sphingolipids are essential for differentiation but not growth in Leishmania.

@nl

P1433

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P1433

The EMBO Journal

P1476

Sphingolipids are essential for differentiation but not growth in Leishmania

@en

P2093

Fong-Fu Hsu

http://www.w3.org/2001/XMLSchema#string

Javier Revollo

http://www.w3.org/2001/XMLSchema#string

John Turk

http://www.w3.org/2001/XMLSchema#string

Kai Zhang

http://www.w3.org/2001/XMLSchema#string

Melissa Showalter

http://www.w3.org/2001/XMLSchema#string

P2860

Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation

Functional rafts in cell membranes

Characterization of enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity

Involvement of long chain fatty acid elongation in the trafficking of secretory vesicles in yeast

Receptor downregulation and multivesicular-body sorting

Lipid rafts and signal transduction

The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind

Functions of lipid rafts in biological membranes

GPI-anchored proteins and glycoconjugates segregate into lipid rafts in Kinetoplastida.

Possible roles of glycosphingolipids in lipid rafts.

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6016-6026

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scholarly article

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10.1093/EMBOJ/CDG584

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22

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22

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Stephen M. Beverley

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2003-11-01T00:00:00Z

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9015530

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14609948

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275442

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